Raman spectroscopic study of Ni2+–DNA interactions in aqueous systems
文献信息
Janusz Stangret, Rodrigue Savoie
The interactions of Ni2+ ion with calf thymus DNA has been studied in water at metal/DNA phosphate mole ratios ranging from 0.0125 to 6 using Raman spectroscopy. The weighted difference spectra method has been applied to analyze the data. It has been established that Ni2+ ion coordinates mainly at N7 centers of guanine (G) and adenine (A) of DNA at GG, AA and GA sequence places. At the same time the Ni2+ shows outer-sphere interaction, via water molecules, with phosphate groups of DNA.
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来源期刊
Physical Chemistry Chemical Physics

Physical Chemistry Chemical Physics (PCCP) is an international journal co-owned by 19 physical chemistry and physics societies from around the world. This journal publishes original, cutting-edge research in physical chemistry, chemical physics and biophysical chemistry. To be suitable for publication in PCCP, articles must include significant innovation and/or insight into physical chemistry; this is the most important criterion that reviewers and Editors will judge against when evaluating submissions. The journal has a broad scope and welcomes contributions spanning experiment, theory, computation and data science. Topical coverage includes spectroscopy, dynamics, kinetics, statistical mechanics, thermodynamics, electrochemistry, catalysis, surface science, quantum mechanics, quantum computing and machine learning. Interdisciplinary research areas such as polymers and soft matter, materials, nanoscience, energy, surfaces/interfaces, and biophysical chemistry are welcomed if they demonstrate significant innovation and/or insight into physical chemistry. Joined experimental/theoretical studies are particularly appreciated when complementary and based on up-to-date approaches.











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