Probing the mechanism of Prins cyclisations and application to the synthesis of 4-hydroxytetrahydropyrans

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发布日期 2005-06-16

DOI 10.1039/B504562B

影响因子 6.222

作者

Conor S. Barry, Nick Bushby, John R. Harding, Rachael A. Hughes, Gregory D. Parker, Richard Roe, Christine L. Willis

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摘要

Trapping intermediates on the Prins cyclisation pathway with carbon-based nucleophiles has given further insight into factors affecting the acid-mediated reactions of homoallylic alcohols with aldehydes, enabling the design of efficient syntheses of 4-hydroxy-2,6-disubstituted tetrahydropyrans.

期刊推荐

Journal of the American Chemical Society

Biopolymers

Anti-Corrosion Methods and Materials

Advances in Colloid and Interface Science

AIAA Journal

Cement and Concrete Research

Corrosion Science

Chemical & Pharmaceutical Bulletin

Carbon

Chemical Reviews

来源期刊

Chemical Communications

CiteScore: 8.6

自引率: 4.7%

年发文量: 2458

ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry

Probing the mechanism of Prins cyclisations and application to the synthesis of 4-hydroxytetrahydropyrans

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