Microstructure analysis of biocompatible phosphoester copolymers

文献信息

发布日期 2013-06-06

DOI 10.1039/C3PY00563A

影响因子 5.582

作者

Romina Schröder, Sandra Ritz, Frederik R. Wurm

查看原文

摘要

Copolymers with varying compositions of 2-ethoxy-2-oxo-1,3,2-dioxaphospholane (EEP) and 2-ethoxy-4-methyl-2-oxo-1,3,2-dioxaphospholane (EMEP) have been synthesized via 1,5,7-triazabicyclo[4.4.0]dec-5-ene-catalyzed anionic ring-opening polymerization. The molecular weights and comonomer ratios were well controlled and polymers with reasonable molecular weight distributions (<1.5) were obtained in all cases. The copolymers were investigated by 1H and 31P NMR spectroscopies to determine the underlying microstructure via detailed dyad analysis. The copolymers were found to be nontoxic to HeLa cells. Furthermore, the obtained copolymers of EEP and EMEP show thermoresponsive properties, i.e., exhibit a lower critical solution temperature (LCST).

期刊推荐

Letters in Drug Design & Discovery

Natural Product Research

Medicinal Chemistry

Molecular Pharmaceutics

Physics of Life Reviews

Organic & Biomolecular Chemistry

Annual Review of Materials Research

Current Topics in Medicinal Chemistry

Catalysis Surveys from Asia

Current Organic Synthesis

来源期刊

Polymer Chemistry

CiteScore: 8.6

自引率: 7.3%

年发文量: 457

Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.

Microstructure analysis of biocompatible phosphoester copolymers

文献信息

期刊推荐

相关文献

Fluorescence visualization of cucurbit[8]uril-triggered dynamic host–guest assemblies

Correction: Fused ambipolar aza-isoindigos with NIR absorption

3,6-Diamino-7,8-dihydroisoquinoline-4-carbonitrile derivatives: unexpected facile synthesis, full-color-tunable solid-state emissions and mechanofluorochromic activities

Total synthesis of kopsine, fruticosine, and structurally related polycyclic caged Kopsia indole alkaloids

Synthetic developments on the preparation of sulfides from thiol-free reagents

(±)-Pinnatifidaones A–D, four pairs of highly modified neolignan enantiomers with a rare spirocyclohexenone skeleton from Crataegus pinnatifida

Front cover

Combined application of organozinc chemistry and one-pot hydroboration–Suzuki coupling to the synthesis of amino acids

Contents list

Contents list

您可能还喜欢

4-[4-三氟甲基苯基]恶唑(CAS号：1126636-40-5)通常如何合成？

氢溴酸西酞普兰(CAS号：59729-32-7)的主要用途是什么？

RockPhos Pd G3(CAS号：2009020-38-4)通常如何合成？

1-哌啶甲酰胺(CAS号：2158-03-4)的市场或研究趋势如何？

2-(二苯基膦基)乙胺(CAS号：4848-43-5)适用哪些法规指南？

如何储存间苯二甲酸二烯丙酯(CAS号：1087-21-4)？

什么是间甲苯异硫代异氰酸酯(CAS号：621-30-7)？

在合成中是否有N-Boc-D-苯丙氨醇(CAS号：106454-69-7)的替代品？

3-羟甲基-2-氧异丙基吡啶(CAS号：954240-50-7)的主要用途是什么？

6-氨基-9-甲基嘌呤(CAS号：700-00-5)应用于哪些行业？

来源期刊

Polymer Chemistry

推荐化合物

Phenethylmagnesium chloride

Sodium 4-{2-[(E)-2-{(3E)-3-{(2E)-2-[3,3-dimethyl-1-(4-sulfonatobutyl)-1,3-dihydro-2H-indol-2-ylidene]ethylidene}-2-[(4-isothiocyanatophenyl)sulfanyl]-1-cyclohexen-1-yl}vinyl]-3,3-dimethyl-3H-indolium- 1-yl}-1-butanesulfonate

Ethyl (3aS,6aS)-1-benzylhexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylate

Ivangustin

Methyl 2-(5-bromo-2-chlorophenyl)acetate

推荐供应商