Innovative well-defined primary amine-based polyacrylates for plasmid DNA complexation

文献信息

发布日期 2014-06-16

DOI 10.1039/C4PY00585F

影响因子 5.582

作者

Hien The Ho, Sagrario Pascual, Véronique Montembault, Nathalie Casse, Laurent Fontaine

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摘要

Well-defined quaternized poly(2-aminoethyl acrylate)s (qPAEAs) have been synthesized by RAFT polymerization of N-(tert-butoxycarbonyl)aminoethyl acrylate (t-BocAEA) followed by t-Boc group deprotection. The ability of qPAEAs to act as potential “smart” DNA carriers has been shown by plasmid DNA/qPAEA complexation and qPAEA degradation in water at 37 °C without any trigger.

期刊推荐

Organic Process Research & Development

Chemical Communications

Current Opinion in Solid State & Materials Science

Chemistry Education Research and Practice

Drug Discovery Today

Journal of Saudi Chemical Society

Russian Journal of Bioorganic Chemistry

Journal of Natural Medicines

New Journal of Chemistry

Crystallography Reports

来源期刊

Polymer Chemistry

CiteScore: 8.6

自引率: 7.3%

年发文量: 457

Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.

Innovative well-defined primary amine-based polyacrylates for plasmid DNA complexation

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