![(2E)-3-(3-Chlorophenyl)-N-{2-[4-(methylsulfonyl)-1-piperazinyl]-2-oxoethyl}acrylamide structure](https://cnstatic.chemtradehub.com/structs/250/2505001-54-5-c1e9.webp "(2E)-3-(3-Chlorophenyl)-N-{2-[4-(methylsulfonyl)-1-piperazinyl]-2-oxoethyl}acrylamide structure")
Catch and release: photocleavable cationic diblock copolymers as a potential platform for nucleic acid delivery
文献信息
发布日期
2014-06-05
DOI
10.1039/C4PY00638K
影响因子
5.582
作者
Matthew D. Green, Abbygail A. Foster, Chad T. Greco, Raghunath Roy, Rachel M. Lehr, Thomas H. Epps, III, Millicent O. Sullivan
查看原文
摘要
Binding interactions between DNA and cationic nanocarriers must be sufficiently strong to prevent nuclease-mediated degradation, yet weak enough to permit transcription. We demonstrate cationic diblock copolymers containing PEG and o-nitrobenzyl moieties that facilitated tailorable DNA complexation and light-activated release. This design unlocks a new approach to improved non-viral gene packaging.
期刊推荐
Current Opinion in Solid State & Materials Science
Russian Journal of Applied Chemistry
Crystallography Reports
Journal of Peptide Science
Nature Medicine
Journal of Saudi Chemical Society
Saudi Pharmaceutical Journal
Russian Journal of General Chemistry
Russian Journal of Coordination Chemistry
Organic Process Research & Development
相关文献
First-principles study of χ3-borophene for charge-modulated switchable CO2 capture
Wenwei Luo, Hewen Wang, Zhiqiang Wang, Gang Liu, Sanqiu Liu, Chuying Ouyang
2020-03-25
Paper
DOI: 10.1039/D0CP01020K
A detailed description of the CO molecule adsorbed in InOF-1
Bruno Landeros-Rivera, Ilich A. Ibarra, Mariana L. Díaz-Ramírez, Rubicelia Vargas, Hugo A. Lara-García, Jorge Garza, Ana Martínez
2020-03-16
Paper
DOI: 10.1039/D0CP00579G
The mechanism of thiophene oxidation on metal-free two-dimensional hexagonal boron nitride
Naixia Lv, Linghao Sun, Linlin Chen, Yujun Li, Jinrui Zhang, Peiwen Wu, Hongping Li, Wenshuai Zhu, Huaming Li
2019-09-18
Paper
DOI: 10.1039/C9CP03758F
BAR-based multi-dimensional nonequilibrium pulling for indirect construction of QM/MM free energy landscapes: from semi-empirical to ab initio
2019-09-25
Paper
DOI: 10.1039/C9CP04113C
Dissociation dynamics in low energy electron attachment to ammonia using velocity slice imaging
Dipayan Chakraborty, Aranya Giri, Dhananjay Nandi
2019-09-09
Paper
DOI: 10.1039/C9CP03973B
How do mutations affect the structural characteristics and substrate binding of CYP21A2? An investigation by molecular dynamics simulations
Baihui Lin, Hongxing Zhang
2020-03-27
Paper
DOI: 10.1039/D0CP00763C
Systematic modification of the indium tin oxide work function via side-chain modulation of an amino-acid functionalization layer
Naomi Kramer, Soumyajit Sarkar, Leeor Kronik, Nurit Ashkenasy
2019-09-23
Paper
DOI: 10.1039/C9CP04079J
Allosteric modulation of the sarcoplasmic reticulum Ca2+ ATPase by thapsigargin via decoupling of functional motions
Noureldin Saleh, Yong Wang, Poul Nissen, Kresten Lindorff-Larsen
2019-09-17
Paper
DOI: 10.1039/C9CP04736K
Ternary 12-electron CBe3X3+ (X = H, Li, Na, Cu, Ag) clusters: planar tetracoordinate carbons and superalkali cations
Lin-Yan Feng, Chuan Dong, Hua-Jin Zhai
2019-09-12
Paper
DOI: 10.1039/C9CP04437J
Holistic approach to chemical degradation of Nafion membranes in fuel cells: modelling and predictions
Philipp Frühwirt, Jens T. Törring, Tomaž Katrašnik, Georg Gescheidt
2020-02-26
Paper
DOI: 10.1039/C9CP04986J
您可能还喜欢
化合物问答
如何储存1,2-环己二酮环乙缩醛(CAS号：4746-96-7)？
1,2-环己二酮环乙缩醛应储存在阴凉、干燥、通风良好的地方，避免阳光直射。建议使用密封容器保存，并保持环境温度在室温范围内，远离火源和热源。
4746-96-71,4-Dioxaspiro[4.5]d...
化合物问答
Ecopladib(CAS号：381683-92-7)的市场或研究趋势如何？
Ecopladib作为一种新型的药物，主要应用于治疗高胆固醇等疾病。目前，市场和研究趋势显示，Ecopladib因其独特的药理作用而受到关注。随着对心血管疾病治...
381683-92-7Ecopladib
化合物问答
2,3-Dimethyl-3H-imidazo[4,5-c]pyridine(CAS号：52538-09-7)通常如何合成？
2,3-二甲基-3H-咪唑[4,5-c]吡啶通常通过咪唑和2,3-二甲基吡啶的缩合反应合成。具体来说，将咪唑和2,3-二甲基吡啶在适当的溶剂中进行加热或加压反应...
52538-09-72,3-Dimethyl-3H-imid...
化合物问答
2,3,4,5-tetrahydro-1H-3-苯并氮杂环;盐酸盐(CAS号：17379-01-0)的市场或研究趋势如何？
该化合物在药物化学和有机合成中有一定的应用。近年来，随着对新型药物化合物的需求增加，该化合物的研究趋势主要集中在探索其生物活性，尤其是其在神经系统疾病治疗中的潜...
17379-01-02,3,4,5-Tetrahydro-1...
68-90-6(2-Ethyl-1-benzofura...
化合物问答
如何储存盐酸甘氨酸丁酯(CAS号：13048-99-2)？
盐酸甘氨酸丁酯应储存在阴凉、干燥、通风良好的地方，避免阳光直射和高温环境，温度应控制在25℃以下。储存容器应密封，避免与空气中的水分和酸性物质接触，以防发生水解...
13048-99-2Butyl glycinate hydr...
化合物问答
什么是2-Iodo-N,N-dimethylbenzamide(CAS号：54616-46-5)？
2-碘-N,N-二甲基苯胺是一种有机化合物，化学名为2-Iodo-N,N-dimethylbenzamide。其分子式为C<sub>9</sub>H<sub>1...
54616-46-52-Iodo-N,N-dimethylb...
16817-90-6N-Cyclohexylglycinam...
化合物问答
5-溴-2-(4H-1,2,4-三唑-4-基)吡啶(CAS号：959240-99-4)的市场或研究趋势如何？
随着医药、农药和新材料领域的发展，该化合物作为关键中间体的应用日益增多。特别是在药物合成中，由于其独特的化学性质，可以用于合成多种药物分子。未来的研究趋势可能集...
959240-99-45-Bromo-2-(4H-1,2,4-...
化合物问答
2,4-二溴-6-三氟甲基嘧啶(CAS号：785778-00-9)通常如何合成？
2,4-二溴-6-三氟甲基嘧啶通常通过溴化反应合成。首先，将6-三氟甲基嘧啶与溴化剂（如液溴）在适当的溶剂（如二氯甲烷、四氢呋喃）中反应，加入适当的催化剂（如四...
785778-00-92,4-Dibromo-6-(trifl...
来源期刊
Polymer Chemistry
CiteScore:
8.6
自引率:
7.3%
年发文量:
457
Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.
推荐化合物
![N-[2-(4-Hydroxyphenoxy)-4-nitrophenyl]methanesulfonamide structure](https://cnstatic.chemtradehub.com/structs/109/109032-22-6-7c88.webp "N-[2-(4-Hydroxyphenoxy)-4-nitrophenyl]methanesulfonamide structure")
推荐供应商
免责声明
本页面提供的学术期刊信息仅供参考和研究使用。我们与任何期刊出版商均无关联，也不处理投稿事宜。如有投稿相关咨询，请直接联系相关期刊出版商。
如发现页面信息有误，请发送邮件至 support@chemtradehub.com 联系我们。我们将及时核实并处理您的问题。