Far-red/near-infrared fluorescent conjugated polymer nanoparticles with size-dependent chirality and cell imaging applications
文献信息
发布日期
2015-04-13
DOI
10.1039/C5PY00344J
影响因子
5.582
作者
Chunhui Dai, Dongliang Yang, Wenjie Zhang, Biqing Bao, Yixiang Cheng, Lianhui Wang
查看原文
摘要
A novel chiral conjugated polymer is developed and used for the preparation of conjugated polymer nanoparticles (CPNs) with particle sizes ranging from 80 to 190 nm. The size-dependent optical properties of chiral CPNs are fully studied and it was found that the nanoparticles exhibited a prominent red shift both in UV-vis and fluorescence emission with increasing diameters. The circular dichroism (CD) spectra and anisotropy r values of the CPNs display size-tunable chirality features, which can be attributed to the nature of the aggregates as nanoparticles grow. Meanwhile, the obtained CPNs can serve as efficient far-red/near-infrared (FR/NIR) fluorescent probes with low cytotoxicity and high photostability for HeLa cell imaging.
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来源期刊
Polymer Chemistry
CiteScore:
8.6
自引率:
7.3%
年发文量:
457
Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.
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