![6-(Benzyloxy)-8-(2-bromoacetyl)-2H-benzo[b][1,4]oxazin-3(4H)-one structure](https://cnstatic.chemtradehub.com/structs/926/926319-53-1-2287.webp "6-(Benzyloxy)-8-(2-bromoacetyl)-2H-benzo[b][1,4]oxazin-3(4H)-one structure")
Fluorescent and “breathable” CO2 responsive vesicles inspired from green fluorescent protein
文献信息
发布日期
2017-09-21
DOI
10.1039/C7PY00963A
影响因子
5.582
作者
Lei Xu, Ning Ren, Ji Pang, Hongping Deng, Xinyuan Zhu, Mo Sun, Deyue Yan
查看原文
摘要
The design of green fluorescent protein (GFP) chromophore labeled, CO2 responsive vesicles that can mimic the breathing of jellyfish is described. The vesicles were obtained via the self-assembly of a di-block copolymer bearing a hydrophilic poly(ethylene glycol) (PEG) segment and a hydrophobic, CO2 responsive poly((diethylamino)ethyl methacrylate) (PDEAEMA) segment, with a GFP chromophore between the two blocks. Like the breathing of a jellyfish, the vesicles’ size and fluorescence changed significantly upon exposure to CO2, as confirmed by morphology observation and fluorescence measurements. Further analysis suggested that the “breathing” of the vesicles is reversible under a continuous CO2/N2 gas flow. The “breathing” behavior of the fluorescent vesicles was also directly observable under a confocal microscope.
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来源期刊
Polymer Chemistry
CiteScore:
8.6
自引率:
7.3%
年发文量:
457
Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.
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