Self-assembly of random co-polymers for selective binding and detection of peptides

文献信息

发布日期 2017-12-19

DOI 10.1039/C7PY01947E

影响因子 5.582

作者

Bo Zhao, Mahalia A. C. Serrano, Jingjing Gao, Jiaming Zhuang

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摘要

Amphiphilic random co-polymers, which form stable reverse micelle-type assemblies, have been designed and synthesized. We demonstrate that the reverse micelles, formed by these co-polymers are capable of selectively binding peptides through electrostatic interactions, indicating that these random polymers can self-organize into functionally selective materials. Moreover, these random co-polymers also enable the ordered co-crystallization of matrix and extract guest molecules, giving rise to substantial signal enhancements during MALDI-MS detection. Together, these observations represent an excellent example of how random polymers can self-assemble into ordered, functional materials.

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Main Group Metal Chemistry

Computational Materials Science

Diamond and Related Materials

Advances in Cement Research

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Chemistry of Materials

Composite Interfaces

Journal of Physical Organic Chemistry

Advanced Materials

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来源期刊

Polymer Chemistry

CiteScore: 8.6

自引率: 7.3%

年发文量: 457

Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.

Self-assembly of random co-polymers for selective binding and detection of peptides

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来源期刊

Polymer Chemistry

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