A fluorescent probe based on a Tb3+/Cu2+ co-functionalized MOF for urinary sarcosine detection

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发布日期 2018-04-04

DOI 10.1039/C8AN00425K

影响因子 4.616

作者

Na-Na Sun, Bing Yan

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摘要

A novel luminescent probe based on a Tb3+/Cu2+ heterometallic metal–organic framework (MOF) was first designed for beamed monitoring of urinary sarcosine, a differential metabolite that can indicate the progression of prostate cancer (PCa). The fluorescent probe presented high selectivity towards sarcosine in urine. It also displayed good sensitivity with a comparatively low detection limit and a fast response to sarcosine within 5 min. Moreover, such high selectivity and sensitivity towards sarcosine is not subject to interference from other coexisting species in urine. At the same time, this fluorescent material also demonstrated the possibility for recycling. The excellent sensing performance of this Ln-MOF (lanthanide MOF) enables it to be further employed as a serviceable tool for PCa diagnosis and monitoring.

期刊推荐

Doklady Chemistry

Anti-Corrosion Methods and Materials

Journal of the Chinese Chemical Society

Canadian Metallurgical Quarterly

Australian Journal of Chemistry

Chemistry of Natural Compounds

Journal of the American Chemical Society

Chemistry of Heterocyclic Compounds

Bulletin of the Chemical Society of Japan

Carbon

来源期刊

Analyst

CiteScore: 7.8

自引率: 5.6%

年发文量: 653

Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.

A fluorescent probe based on a Tb3+/Cu2+ co-functionalized MOF for urinary sarcosine detection

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