Asymmetric domino 1,6-addition/annulation reaction of 3-cyano-4-alkenyl-2H-chromen-2-ones with isatin-derived MBH carbonates: enantioselective synthesis of 3,3′-cyclopentenylspirooxindoles bearing 2H-chromen-2-ones
文献信息
Zhen-Hua Wang, Chuan-Wen Lei, Xia-Yan Zhang, Yong You, Jian-Qiang Zhao
An asymmetric domino 1,6-addition/annulation reaction of 3-cyano-4-alkenyl-2H-chromen-2-ones with isatin-derived MBH carbonates was achieved. With this developed protocol, a series of 3,3′-cyclopentenylspirooxindoles bearing 2H-chromen-2-ones were obtained in moderate to excellent yields with good to excellent diastereo- and enantioselectivities (>20 : 1 dr, up to 97 : 3 er).
期刊推荐

Russian Journal of Applied Chemistry

Chemical Communications

Acta Materialia

Russian Journal of Coordination Chemistry

Chemistry Education Research and Practice

Current Opinion in Colloid & Interface Science

Russian Journal of Organic Chemistry

Russian Journal of Bioorganic Chemistry

Current Opinion in Solid State & Materials Science

Crystallography Reports
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Organic Chemistry Frontiers

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