Visible-light-induced radical hydrodifluoromethylation of alkenes
文献信息
Jiao Yu, Jin-Hong Lin, Yu-Cai Cao, Ji-Chang Xiao
Described here is the radical-mediated hydrodifluoromethylation of alkenes that occurs under transition-metal-free conditions by using the phosphonium salt [Ph3P+CF2H]Br− under the irradiation of 26 W household compact fluorescent light. The reaction lends itself to a convenient protocol for the installation of a C–CF2H bond while maintaining good functional group tolerance.
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Organic Chemistry Frontiers

Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry




