Pd-Catalyzed multicomponent reaction of sulfonyl azides, primary amines and methyl α-isocyanoacetates: highly efficient synthesis of tetrasubstituted imidazolone derivatives
文献信息
Fei Wang, Pei Xu, Bei-Bei Liu, Shun-Yi Wang, Shun-Jun Ji
A highly efficient Pd-catalyzed multicomponent reaction of sulfonyl azides, primary amines and methyl α-isocyanoacetates was developed. This method provided an efficient and simple strategy for the synthesis of tetrasubstituted imidazolone derivatives in good to excellent yields via sulfonyl guanidine intermediates. This protocol shows a broad substrate scope and mild reaction conditions, and new C–C, and C–N bonds were constructed via a three-component reaction in one step.
期刊推荐

Journal of Natural Medicines

Saudi Pharmaceutical Journal

Russian Journal of Coordination Chemistry

Chemical Communications

Journal of Saudi Chemical Society

Crystallography Reports

Drug Discovery Today

Current Opinion in Solid State & Materials Science

Russian Journal of Applied Chemistry

New Journal of Chemistry
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Organic Chemistry Frontiers

Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry




