Oxidative N-heterocyclic carbene-catalyzed [3 + 3] annulation reaction of enals with benzofuran-3-ones: efficient access to benzofuran-fused δ-lactones
文献信息
Zhan-Yong Wang, Ting Yang, Kai-Kai Wang, Rongxiang Chen, Menghan Liu
A facile route to benzofuran-fused δ-lactones was developed via an N-heterocyclic carbene-catalyzed [3 + 3] annulation reaction, giving the expected products in high yields (up to 99%) with excellent enantioselectivities (up to 98% ee). It should be noted that benzofuran-fused pyrones can be obtained stepwise in one pot with excellent yields (up to 96%) by using this methodology.
相关文献
Topology vs. thermodynamics in chemical reactions: the instability of PH5
Christian Tantardini
DOI: 10.1039/C7CP06130G
Theoretical investigation of the solid–liquid phase transition in protonated water clusters
Kseniia Korchagina, Aude Simon, Mathias Rapacioli, Fernand Spiegelman, Jean-Marc L’Hermite, Isabelle Braud, Sébastien Zamith, Jérôme Cuny
DOI: 10.1039/C7CP04863G
Dynamics of the crystal structure of tin-based type-I clathrates with different degrees of disorder in their cationic frameworks
V. V. Novikov, K. S. Pilipenko, A. V. Matovnikov, N. V. Mitroshenkov, B. I. Kornev
DOI: 10.1039/C7CP05023B
Vacuum ultraviolet photoabsorption spectroscopy of crystalline and amorphous benzene
Anita Dawes, Søren V. Hoffmann, Nykola C. Jones, Nigel J. Mason
DOI: 10.1039/C7CP05319C
The ionic versus metallic nature of 2D electrides: a density-functional description
Stephen G. Dale, Erin R. Johnson
DOI: 10.1039/C7CP04825D
Effects of H+ and OH− on H2O as probed by the 1-propanol probing methodology: differential thermodynamic approach
Yoshikata Koga, Kumiko Miki, Keiko Nishikawa
DOI: 10.1039/C7CP05519F
Hybrid heterojunctions between a 2D transition metal dichalcogenide and metal phthalocyanines: their energy levels vis-à-vis current rectification
Arnab Banerjee, Biswajit Kundu, Amlan J. Pal
DOI: 10.1039/C7CP05470J
Study of the interaction between cisplatin and the Au18(SR)14 cluster: in search of an appropriate cisplatin carrier
O. Palacios-Álvarez, A. Tlahuice-Flores
DOI: 10.1039/C7CP04452F
您可能还喜欢
如何处理含有8-氯咪唑并[1,2-A]吡嗪(CAS号:69214-33-1)的废料?
处理含有8-氯咪唑并[1,2-A]吡嗪的废料时,应首先将其收集并进行化学回收或降解。如果无法回收,需采用安全的化学处理方法,如中和、氧化还原或沉淀。处理过程中需...
Calhex 231 hydrochloride(CAS号:2387505-78-2)适用哪些法规指南?
Calhex 231 hydrochloride 需要遵循《全球化学品统一分类和标签制度》(GHS)的分类和标签要求,以及欧盟的《化学品注册、评估、授权和限制条...
11-Beta,17-alpha,21-三羟基-5-beta-孕烯-3,20-二酮(CAS号:1482-50-4)的物理化学性质是什么?
11-Beta,17-alpha,21-三羟基-5-beta-孕烯-3,20-二酮是一种无色结晶性粉末,分子量为372.45 g/mol。该化合物在水中的溶解度...
处理5-异丙基-1,3,4-恶二唑-2-羧酸(CAS号:944907-13-5)时应注意哪些实验室安全事项?
处理5-异丙基-1,3,4-恶二唑-2-羧酸时应注意以下安全事项:穿戴适当的个人防护装备,包括实验室外套、手套和护目镜;操作应在通风橱中进行,以减少吸入或接触有...
benzyl 3-bromopropanoate(CAS号:90841-55-7)安全吗?
Benzyl 3-bromopropanoate属于有毒物质,吸入、摄入或皮肤接触均可能对人体造成伤害。操作时应佩戴防护眼镜、口罩和手套,避免吸入蒸汽和直接接触...
什么是(R)-N-苄氧羰基-3,4-二氢-1H-异喹啉羧酸(CAS号:151004-88-5)?
(R)-N-苄氧羰基-3,4-二氢-1H-异喹啉羧酸是一种含有苄氧羰基和异喹啉环结构的化合物,分子式为C17H15NO3。它是一种有机化合物,具有一定的生物活性...
在合成中是否有1-苄基吡啶嗡-3-羧酸盐(CAS号:15990-43-9)的替代品?
可以考虑使用1-苄基吡啶-3-羧酸盐作为1-苄基吡啶嗡-3-羧酸盐的替代品。此外,还可以探索其他类似物,如1-苄基吡啶-3-氨基甲酸酯等。具体的替代品选择需根据...
(2,6-二甲基吡啶-3-基)甲醇(CAS号:582303-10-4)安全吗?
(2,6-二甲基吡啶-3-基)甲醇在使用时需注意安全,应避免吸入其蒸汽,接触皮肤和眼睛。操作应在通风良好的环境中进行,佩戴适当的个人防护装备。
5-溴-2-乙烯基吡啶(CAS号:226883-52-9)的物理化学性质是什么?
5-溴-2-乙烯基吡啶是一种有机化合物,外观为白色固体,具有良好的结晶性。分子量约为190.03 g/mol。它的溶解性在水中较差,但在有机溶剂如二氯甲烷、甲醇...
2-羟基-3-硝基-5-甲基吡啶(CAS号:7464-14-4)应用于哪些行业?
2-羟基-3-硝基-5-甲基吡啶主要应用于医药、聚合物和半导体行业。在医药领域,它可以用作合成其他药物的中间体。在聚合物领域,它可以作为功能性单体参与聚合反应,...
来源期刊
Organic Chemistry Frontiers

Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry











![N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-beta-phenyl-L-phenylalanine structure N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-beta-phenyl-L-phenylalanine structure](https://cnstatic.chemtradehub.com/structs/201/201484-50-6-c2fc.webp)


