![N-[(5,6-Dichloro-1H-benzimidazol-2-yl)methyl]-9-(1-methyl-1H-pyrazol-4-yl)-2-(4-morpholinyl)-9H-purin-6-amine structure](https://cnstatic.chemtradehub.com/structs/238/2387704-62-1-25f4.webp "N-[(5,6-Dichloro-1H-benzimidazol-2-yl)methyl]-9-(1-methyl-1H-pyrazol-4-yl)-2-(4-morpholinyl)-9H-purin-6-amine structure")
Chiral strong Brønsted acid-catalyzed enantioselective addition reaction of simple olefins with ethyl glyoxylate
文献信息
发布日期
2020-04-28
DOI
10.1039/D0QO00448K
影响因子
5.281
作者
Jun Kikuchi, Yuki Aizawa, Masahiro Terada
查看原文
摘要
An enantioselective intermolecular carbonyl–ene reaction and a Friedel–Crafts-type reaction of 1,1,2-trisubstituted and 1,2-disubstituted simple olefins with ethyl glyoxylate were developed using F10BINOL-derived N-sulfonyl phosphoramide as the chiral strong Brønsted acid catalyst. The present reactions feature an atom-economical and environmentally benign approach to the synthesis of enantioenriched allylic and homoallylic alcohols.
期刊推荐
Science Progress
Kinetics and Catalysis
Proceedings of the National Academy of Sciences of the United States of America
European Journal of Wood and Wood Products
Nature
Fibre Chemistry
Organic Preparations and Procedures International
Russian Chemical Reviews
Pharmacological Reviews
Journal of Heterocyclic Chemistry
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来源期刊
Organic Chemistry Frontiers
CiteScore:
7.8
自引率:
8.7%
年发文量:
724
Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry
推荐化合物
4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)morpholine
CAS号:
485799-04-0
分子式:
C15H23BN2O3
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