Dinuclear osmium complexes as mitochondrion-targeting antitumor photothermal agents in vivo

文献信息

发布日期 2022-10-18

DOI 10.1039/D2CC05230J

影响因子 6.222

作者

Meng-Fan Wang, Yu-Ang Deng, Qing-Fang Li, Shi-Jie Tang, Rong Yang, Run-Yu Zhao, Fu-Dan Liu, Xiaoxia Ren, Dan Zhang, Feng Gao

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摘要

Four dinuclear osmium complexes have been constructed for antitumor phototherapy. The most potent Os4 has extremely high photothermal conversion capability under irradiation of an 808 nm low-power laser, targets mitochondria in human melanoma cells without nucleus affinity, and acts as an antitumor photothermal therapy agent in vitro and in vivo.

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来源期刊

Chemical Communications

CiteScore: 8.6

自引率: 4.7%

年发文量: 2458

ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry

Dinuclear osmium complexes as mitochondrion-targeting antitumor photothermal agents in vivo

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