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1-{[(4R,7S,10S,13S,16S,19R)-19-Amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-p rolyl-L-arginylglycinamide(CAS: 113-79-1)
![1-{[(4R,7S,10S,13S,16S,19R)-19-Amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-p
rolyl-L-arginylglycinamide](https://cnstatic.chemtradehub.com/structs/113/113-79-1-026f.webp "1-{[(4R,7S,10S,13S,16S,19R)-19-Amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-p
rolyl-L-arginylglycinamide")
CAS号
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(4S)-4-amino-5-[[(1S)-2-[[(1S)-1-[[(1S)-2-[[(1S)-2-[[(1S)-2-[[2-[[(1S)-2-[[(1S)-1-[[(1S)-1-[[(1S)-2-[[(1S)-2-[[(1S)-4-amino-1-[[(1S)-5-amino-1-[[(1S)-1-[[(1S)-1-[[(1S)-2-[[(1S)-2-[[(1S)-2-[[(1S)-1-[[(1S)-2-[[(1S)-1-[[2-[[(1S)-2-[[(1S)-3-amino-1-[[(1S)-5-amino-1-[[2-[[(1S)-2-[[(1S,2S)-1-[[(1S,2S)-1-[[2-[[(1S)-1-[[(1S)-1-[[(1S)-1-[[2-[[2-[[(1S)-1-[[(1S)-1-[[(1S,2S)-1-[[(1S)-1-carboxyethyl]carbamoyl]-2-methyl-butyl]carbamoyl]-2-methyl-propyl]carbamoyl]-2-methyl-propyl]amino]-2-oxo-ethyl]amino]-2-oxo-ethyl]carbamoyl]-2-methyl-propyl]carbamoyl]-3-methylsulfanyl-propyl]carbamoyl]-3-methyl-butyl]amino]-2-oxo-ethyl]carbamoyl]-2-methyl-butyl]carbamoyl]-2-methyl-butyl]amino]-1-methyl-2-oxo-ethyl]amino]-2-oxo-ethyl]carbamoyl]pentyl]carbamoyl]-3-oxo-propyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]amino]-2-oxo-ethyl]carbamoyl]-2-methyl-propyl]amino]-1-(carboxymethyl)-2-oxo-ethyl]carbamoyl]-3-carboxy-propyl]amino]-1-methyl-2-oxo-ethyl]amino]-1-benzyl-2-oxo-ethyl]amino]-1-benzyl-2-oxo-ethyl]carbamoyl]-2-methyl-propyl]carbamoyl]-3-methyl-butyl]carbamoyl]pentyl]carbamoyl]-4-oxo-butyl]amino]-1-(1H-imidazol-4-ylmethyl)-2-oxo-ethyl]amino]-1-(1H-imidazol-4-ylmethyl)-2-oxo-ethyl]carbamoyl]-2-methyl-propyl]carbamoyl]-3-carboxy-propyl]amino]-1-[(4-hydroxyphenyl)methyl]-2-oxo-ethyl]amino]-2-oxo-ethyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]amino]-1-(carboxymethyl)-2-oxo-ethyl]amino]-1-(1H-imidazol-4-ylmethyl)-2-oxo-ethyl]carbamoyl]-4-guanidino-butyl]amino]-1-benzyl-2-oxo-ethyl]amino]-5-oxo-pentanoic acid
CAS号: 157884-74-7
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其他供应商提供的 1-{[(4R,7S,10S,13S,16S,19R)-19-Amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-p rolyl-L-arginylglycinamide
![1-{[(4R,7S,10S,13S,16S,19R)-19-Amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-p
rolyl-L-arginylglycinamide — 上海创赛科技有限公司](https://cnstatic.chemtradehub.com/suppliers/67cecce82b2de6e8e95a5e02/67cecce82b2de6e8e95a5e02-logo.webp){kind=logo}
![1-{[(4R,7S,10S,13S,16S,19R)-19-Amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-p
rolyl-L-arginylglycinamide — 赫澎（上海）生物科技有限公司](https://cnstatic.chemtradehub.com/suppliers/67ceccf22b2de6e8e95a5e0f/67ceccf22b2de6e8e95a5e0f-logo.webp){kind=logo}
![1-{[(4R,7S,10S,13S,16S,19R)-19-Amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-p
rolyl-L-arginylglycinamide — 上海绩祥生物科技有限公司](https://cnstatic.chemtradehub.com/suppliers/67ce6f4d2b2de6e8e95a45bf/67ce6f4d2b2de6e8e95a45bf-logo.webp){kind=logo}
![1-{[(4R,7S,10S,13S,16S,19R)-19-Amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-p
rolyl-L-arginylglycinamide — 湖北成海化工有限公司](https://cnstatic.chemtradehub.com/suppliers/67ce17ff57537e5c8069b2e9/67ce17ff57537e5c8069b2e9-logo.webp){kind=logo}
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rolyl-L-arginylglycinamide — 西安壹辉生物科技有限公司](https://cnstatic.chemtradehub.com/suppliers/67cdf26b57537e5c8069afe8/67cdf26b57537e5c8069afe8-logo.webp){kind=logo}
![1-{[(4R,7S,10S,13S,16S,19R)-19-Amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-p
rolyl-L-arginylglycinamide — 湖北永阔科技有限公司](https://cnstatic.chemtradehub.com/suppliers/67cecc092b2de6e8e95a5bbd/67cecc092b2de6e8e95a5bbd-logo.webp){kind=logo}
基本信息
分子式
C46H65N15O12S2
分子量
1084.25 g/mol
Physical Properties
密度
1.59
闪点
113℃
化学标识符
SMILES
C1CC(N(C1)C(=O)C2CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)N)C(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)N
InChIKey
KBZOIRJILGZLEJ-LGYYRGKSSA-N
数据库引用
MDL号
MFCD00076738
常见问题
精氨酸加压素是由九个氨基酸组成的肽类激素，化学名称为1-{[(4R,7S,10S,13S,16S,19R)-19-Amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-L-arginylglycinamide。其分子结构包含多个氨基、酮基和硫醚基团，具有独特的环状结构，主要通过调节肾脏对水的重吸收来维持体液平衡。
精氨酸加压素主要用于治疗中枢性尿崩症和夜间遗尿症，通过抑制抗利尿激素（ADH）的分泌来减少尿液生成。此外，其衍生物如去氨加压素常用于调节血压和治疗某些类型的水肿。在实验研究中，该化合物也作为神经递质受体的靶点用于药物开发。
精氨酸加压素在医疗应用中需严格遵循剂量指导，短期使用通常安全，但可能引起低钾血症、脱水或过敏反应。操作时应佩戴防护手套和护目镜，避免接触眼睛、皮肤及吸入粉尘。若误服或过量使用，可能导致严重健康风险，需及时就医处理。
精氨酸加压素应储存于阴凉干燥处，避光保存，密封防潮。建议在2-8℃低温条件下存放，避免高温加速降解。储存环境需保持相对湿度低于60%，并远离强酸、强碱及氧化剂。使用时需注意防潮、避光，确保药品稳定性。
安全须知
使用前请验证产品规格和安全数据。联系供应商获取详细安全信息。
请始终遵循正确的操作程序
