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(1S,3S)-3-Glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-alpha-L-lyxo-hexopyranoside(CAS: 72496-41-4)
![(1S,3S)-3-Glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-alpha-L-lyxo-hexopyranoside](https://cnstatic.chemtradehub.com/structs/724/72496-41-4-5a94.webp "(1S,3S)-3-Glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-alpha-L-lyxo-hexopyranoside")
CAS号
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其他供应商提供的 (1S,3S)-3-Glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-alpha-L-lyxo-hexopyranoside
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基本信息
分子式
C32H37NO12
分子量
466.49 g/mol
Physical Properties
熔点
188-192°C (dec.)
化学标识符
SMILES
O=CC1CC(OC2CCCC(O2)C)c2c(C1)c(O)c1c(c2O)C(=O)c2c(C1=O)cccc2OC
InChIKey
KMSKQZKKOZQFFG-YXRRJAAWSA-N
数据库引用
MDL号
MFCD00869742
常见问题
吡柔比星是一种蒽醌类抗生素，化学名称为(1S,3S)-3-Glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-alpha-L-lyxo-hexopyranoside。其结构包含一个蒽醌环和一个糖基部分，具有较强的抗癌活性，常用于肿瘤治疗。该化合物通过干扰DNA复制和转录，抑制癌细胞的增殖，属于蒽环类药物的一种。
吡柔比星主要用于治疗多种恶性肿瘤，包括乳腺癌、卵巢癌、肺癌和白血病等。其作用机制是通过与DNA结合，阻止癌细胞的分裂和增殖，同时还能干扰RNA合成。该药物通常作为化疗方案的一部分，与其他药物联合使用以提高疗效。
吡柔比星虽然具有显著的抗癌效果，但使用时需谨慎，因其可能引起严重的副作用，如心脏毒性、骨髓抑制、恶心和呕吐等。使用过程中应密切监测患者的心功能和血液指标，避免过量使用。操作时应佩戴防护手套和护目镜，防止接触皮肤或吸入粉尘，确保安全。
吡柔比星应储存在阴凉、干燥、避光的环境中，通常在2-8°C的低温条件下保存。避免与潮湿空气接触，防止吸湿结块。建议使用密封容器存放，并远离强酸、强碱和其他易反应物质。储存时应避免直接暴露在阳光下，以保持其稳定性与药效。
安全须知
使用前请验证产品规格和安全数据。联系供应商获取详细安全信息。
请始终遵循正确的操作程序