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methyl (3Z)-3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}amino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate(CAS: 656247-17-5)
![methyl (3Z)-3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}amino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate](https://cnstatic.chemtradehub.com/structs/656/656247-17-5-8c09.webp "methyl (3Z)-3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}amino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate")
CAS号
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其他供应商提供的 methyl (3Z)-3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}amino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate
![methyl (3Z)-3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}amino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate — 上海源叶生物科技有限公司](https://cnstatic.chemtradehub.com/suppliers/67ce9f132b2de6e8e95a48fe/67ce9f132b2de6e8e95a48fe-logo.webp){kind=logo}
![methyl (3Z)-3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}amino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate — 常州卡博化工有限公司](https://cnstatic.chemtradehub.com/suppliers/67cec1392b2de6e8e95a4c85/67cec1392b2de6e8e95a4c85-logo.webp){kind=logo}
![methyl (3Z)-3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}amino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate — 江苏开元医药化工有限公司](https://cnstatic.chemtradehub.com/suppliers/67ceb94f2b2de6e8e95a4afa/67ceb94f2b2de6e8e95a4afa-logo.webp){kind=logo}
![methyl (3Z)-3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}amino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate — 北京安必奇生物科技有限公司](https://cnstatic.chemtradehub.com/suppliers/67cecf1f2b2de6e8e95a6382/67cecf1f2b2de6e8e95a6382-logo.webp){kind=logo}
基本信息
分子式
C31H33N5O4
分子量
539.64 g/mol
Physical Properties
沸点
742.199°C at 760 mmHg
化学标识符
SMILES
COC(=O)c1ccc2/C(=C(/Nc3ccc(cc3)N(C)C(=O)CN4CCN(C)CC4)\c5ccccc5)/C(=O)Nc2c1
InChIKey
XZXHXSATPCNXJR-ZIADKAODSA-N
数据库引用
MDL号
MFCD11974012
常见问题
BIBF 1120是一种化学合成化合物，其系统命名为甲基(3Z)-3-[(4-[N-甲基-2-(4-甲基哌嗪-1-基)乙酰氨基]苯基氨基)苯基甲基亚氨基]-2-氧代-2,3-二氢-1H-吲哚-6-甲酸酯。该化合物属于多靶点酪氨酸激酶抑制剂，常用于药物研发领域，特别是抗癌靶点研究。
BIBF 1120主要用于作为研究工具化合物，用于探索其对多种酪氨酸激酶（如VEGFR、PDGFR、FGFR等）的抑制作用。它在体外实验中被广泛用于癌症相关信号通路的研究，帮助开发靶向治疗药物。
BIBF 1120作为研究化合物，其安全性需根据实验条件评估。文献显示其具有一定的细胞毒性，可能对实验人员造成刺激性影响。操作时需佩戴防护手套、护目镜和实验服，避免吸入粉尘。长期或高剂量接触可能对健康产生潜在风险，需遵循实验室安全规范。
BIBF 1120应储存于阴凉、干燥处，避光保存。建议密封于玻璃容器中，置于2-8℃冷藏环境，以防止降解。避免与潮湿空气接触，储存时需远离热源和氧化剂，保持通风良好。
安全须知
使用前请验证产品规格和安全数据。联系供应商获取详细安全信息。
请始终遵循正确的操作程序
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