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(2alpha,5beta,7beta,10beta,13alpha)-4-Acetoxy-1-hydroxy-13-{[(2R,3S)-2-hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-phenylpropanoyl]oxy}-7,10-dimethoxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoa te(CAS: 183133-96-2)
![(2alpha,5beta,7beta,10beta,13alpha)-4-Acetoxy-1-hydroxy-13-{[(2R,3S)-2-hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-phenylpropanoyl]oxy}-7,10-dimethoxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoa
te](https://cnstatic.chemtradehub.com/structs/183/183133-96-2-546b.webp "(2alpha,5beta,7beta,10beta,13alpha)-4-Acetoxy-1-hydroxy-13-{[(2R,3S)-2-hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-phenylpropanoyl]oxy}-7,10-dimethoxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoa
te")
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基本信息
分子式
C45H57NO14
分子量
835.94 g/mol
Physical Properties
熔点
180°C(lit.)
化学标识符
SMILES
CO[C@H]1C[C@H]2OC[C@@]2(OC(=O)C)[C@H]3[C@H](OC(=O)c4ccccc4)[C@]5(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)c6ccccc6)C(=C([C@@H](OC)C(=O)[C@]13C)C5(C)C)C
InChIKey
BMQGVNUXMIRLCK-OAGWZNDDSA-N
数据库引用
MDL号
MFCD18827611
常见问题
卡巴他赛是一种合成的抗癌药物，化学名称为(2alpha,5beta,7beta,10beta,13alpha)-4-乙酰氧基-1-羟基-13-{[(2R,3S)-2-羟基-3-({[(2-甲基-2-丙烷氧基)羰基]氨基}-3-苯基丙烷酰基]氧}-7,10-二甲氧基-9-氧基-5,20-环氧紫杉-11-烯-2-基苯甲酸酯。其分子结构包含多个环状和侧链基团，具有复杂的立体化学特征，属于紫杉烷类化合物的衍生物，常用于癌症治疗领域。
卡巴他赛主要用于治疗多种类型的癌症，如乳腺癌、前列腺癌和非小细胞肺癌等。它通过抑制微管解聚，阻止癌细胞的分裂和增殖，从而发挥抗肿瘤作用。该药物具有良好的抗癌活性，并且在临床试验中显示出优于传统紫杉醇的疗效。
卡巴他赛在正常使用和剂量下是相对安全的，但可能会引起一些副作用，如骨髓抑制、神经毒性以及过敏反应等。因此，在使用过程中需要密切监测患者的血液指标和神经系统状况。此外，操作人员应采取适当的防护措施，如佩戴手套和护目镜，以防止接触和吸入。
卡巴他赛应储存在阴凉、干燥、避光的环境中，建议保存温度为2-8°C。应密封保存以防止受潮，同时避免与空气中的水分或湿气接触。存放时应远离热源和强光，并使用适当的玻璃容器或铝箔包装进行保护。
安全须知
使用前请验证产品规格和安全数据。联系供应商获取详细安全信息。
请始终遵循正确的操作程序
联系信息
联系人
杨
邮箱
394537118@qq.com