化合物问答
磷酸西他列汀(CAS号：654671-77-9)的主要用途是什么？
答案
![(3R)-3-Amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-1-butanone phosphate hydrate (1:1:1)](https://cnstatic.chemtradehub.com/structs/654/654671-77-9-b35b.webp "(3R)-3-Amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-1-butanone phosphate hydrate (1:1:1)")
磷酸西他列汀主要用于治疗2型糖尿病，作为二肽基肽酶-4（DPP-4）抑制剂，能够通过抑制DPP-4酶的活性，延长胰高血糖素样肽-1（GLP-1）和葡萄糖依赖性胰岛素调节多肽（GIP）的半衰期，从而增强胰岛素分泌和降低血糖水平。其作用机制有助于改善胰岛素抵抗，提高胰岛素敏感性，对控制血糖具有显著效果。
关于
CAS号
654671-77-9
英文名称
(3R)-3-Amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-1-butanone phosphate hydrate (1:1:1)
中文名称
磷酸西他列汀
分子式
C16H20F6N5O6P
分子量
523.3270000000001 g/mol
SMILES
C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)CC(CC3=CC(=C(C=C3F)F)F)N.O.OP(=O)(O)O
InChIKey
GQPYTJVDPQTBQC-KLQYNRQASA-N
最后更新: 2025-08-25 01:07
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