化合物问答
什么是索非布韦(CAS号：1190307-88-0)？
答案
![Isopropyl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl)-4-fluoro-3-hydroxy-4-methyltetrahydro-2-furanyl]methoxy}(phenoxy)phosphoryl]amino}propanoate (non-preferred name)](https://cnstatic.chemtradehub.com/structs/119/1190307-88-0-40ef.webp "Isopropyl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl)-4-fluoro-3-hydroxy-4-methyltetrahydro-2-furanyl]methoxy}(phenoxy)phosphoryl]amino}propanoate (non-preferred name)")
索非布韦是一种化学合成药物，其英文名称为Isopropyl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl)-4-fluoro-3-hydroxy-4-methyltetrahydro-2-furanyl]methoxy}(phenoxy)phosphoryl]amino}propanoate。该化合物属于核苷酸类似物，主要用于抗病毒治疗，特别是作为直接抗病毒药物（DAA）治疗慢性丙型肝炎。它通过抑制病毒RNA依赖性RNA聚合酶（NS5B）来阻止病毒复制。
关于
CAS号
1190307-88-0
英文名称
Isopropyl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl)-4-fluoro-3-hydroxy-4-methyltetrahydro-2-furanyl]methoxy}(phenoxy)phosphoryl]amino}propanoate (non-preferred name)
中文名称
索非布韦
分子式
C22H29FN3O9P
分子量
529.4580000000002 g/mol
SMILES
CC(C)OC(=O)[C@H](C)N[P@](=O)(OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@](C)(F)[C@@H]1O)Oc3ccccc3
InChIKey
TTZHDVOVKQGIBA-IQWMDFIBSA-N
最后更新: 2025-08-25 01:08
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