化合物问答
硫酸茛菪素(CAS号：620-61-1)通常如何合成？
答案
![(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl (2S)-3-hydroxy-2-phenylpropanoate sulfate (2:1)](https://cnstatic.chemtradehub.com/structs/620/620-61-1-3fa9.webp "(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl (2S)-3-hydroxy-2-phenylpropanoate sulfate (2:1)")
硫酸茛菪素通常通过合成中间体(3-endo)-8-甲基-8-氮杂双环[3.2.1]辛烷(又称6-甲基-6-氮杂双环[3.2.1]辛烷)与(2S)-3-羟基-2-苯基丙酸的缩合反应得到。该反应通常在酸性催化剂如硫酸的存在下进行，以提高产物的收率和选择性。此外，还存在通过其他中间体的合成方法，但一般产率和选择性较低。
关于
CAS号
620-61-1
英文名称
(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl (2S)-3-hydroxy-2-phenylpropanoate sulfate (2:1)
中文名称
硫酸茛菪素
分子式
C34H48N2O10S
分子量
676.83 g/mol
SMILES
CN1[C@@H]2CC[C@H]1CC(C2)OC(=O)[C@H](CO)C3=CC=CC=C3.CN1[C@@H]2CC[C@H]1CC(C2)OC(=O)[C@H](CO)C3=CC=CC=C3.OS(=O)(=O)O
InChIKey
HOBWAPHTEJGALG-XHJLRQJWSA-N
最后更新: 2025-10-01 21:42
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