化合物问答
N-芴甲氧羰基-N'-(2,2,4,6,7-五甲基二氢苯并呋喃-5-磺酰基)-L-高精氨酸(CAS号：1159680-21-3)通常如何合成？
答案
![L-Lysine, N6-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-](https://cnstatic.chemtradehub.com/structs/115/1159680-21-3-503d.webp "L-Lysine, N6-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-")
该化合物通常通过芴甲氧羰基化反应和二氢苯并呋喃-5-磺酰基化反应合成。首先，将L-高精氨酸与芴甲氧羰氯反应生成芴甲氧羰基-L-高精氨酸，然后将其与2,2,4,6,7-五甲基二氢苯并呋喃-5-磺酰氯反应，得到最终产物。反应需要在无水无氧的条件下进行，产率较高。
关于
CAS号
1159680-21-3
英文名称
L-Lysine, N6-[[[(2,3-dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino]iminomethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-
中文名称
N-芴甲氧羰基-N'-(2,2,4,6,7-五甲基二氢苯并呋喃-5-磺酰基)-L-高精氨酸
分子式
C35H42N4O7S
分子量
662.7956 g/mol
SMILES
O=C(N[C@H](C(=O)O)CCCCNC=NNS(=O)(=O)c1c(C)c(C)c2c(c1C)CC(O2)(C)C)OCC1c2ccccc2c2c1cccc2
InChIKey
ZKHOGJGTGOHNMF-PMERELPUSA-N
最后更新: 2025-10-08 00:58
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