化合物问答
在合成中是否有5'-O-(4,4-二甲氧基三苯甲基)-2'-脱氧-2'-氟尿苷-3'-(2-氰基乙基-N,N-二异丙基)亚磷酰胺(CAS号：146954-75-8)的替代品？
答案
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-2'-fluorouridine](https://cnstatic.chemtradehub.com/structs/146/146954-75-8-07c3.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-2'-fluorouridine")
目前没有完全替代的替代品，但是可以考虑使用类似结构的化合物作为替代物，例如其他类型的官能团修饰的类似结构的核苷或其衍生物。
关于
CAS号
146954-75-8
英文名称
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-2'-fluorouridine
中文名称
5'-O-(4,4-二甲氧基三苯甲基)-2'-脱氧-2'-氟尿苷-3'-(2-氰基乙基-N,N-二异丙基)亚磷酰胺
分子式
C39H46FN4O8P
分子量
748.8 g/mol
SMILES
CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1F)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC
InChIKey
HQHQPAYRJJMYQX-DJTPZYMWSA-N
最后更新: 2025-10-14 19:01
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