化合物问答
蝙蝠葛诺林碱(CAS号：2831-75-6)通常如何合成？
答案
![(1R)-1-[4-(5-{[(1R)-6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydro-1-isoquinolinyl]methyl}-2-hydroxyphenoxy)benzyl]-7-methoxy-2-methyl-1,2,3,4-tetrahydro-6-isoquinolinol](https://cnstatic.chemtradehub.com/structs/283/2831-75-6-aeec.webp "(1R)-1-[4-(5-{[(1R)-6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydro-1-isoquinolinyl]methyl}-2-hydroxyphenoxy)benzyl]-7-methoxy-2-methyl-1,2,3,4-tetrahydro-6-isoquinolinol")
蝙蝠葛诺林碱的合成通常涉及多步反应，包括由6,7-二甲氧基-2-甲基-1,2,3,4-四氢-1-异喹啉甲基提供的中间体与对位含羟基苯酚的衍生物进行偶联反应。通常需要使用过渡金属催化剂如钯或钌来提高合成的选择性和产率。常见的合成步骤包括保护基的引入、官能团转换、后期脱保护等。
关于
CAS号
2831-75-6
英文名称
(1R)-1-[4-(5-{[(1R)-6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydro-1-isoquinolinyl]methyl}-2-hydroxyphenoxy)benzyl]-7-methoxy-2-methyl-1,2,3,4-tetrahydro-6-isoquinolinol
中文名称
蝙蝠葛诺林碱
分子式
C37H42N2O6
分子量
610.7510000000001 g/mol
SMILES
CN1CCC2=CC(=C(C=C2C1CC3=CC=C(C=C3)OC4=C(C=CC(=C4)CC5C6=CC(=C(C=C6CCN5C)OC)OC)O)OC)O
InChIKey
APIHNXDZCYDPTF-FIRIVFDPSA-N
最后更新: 2025-10-19 20:30
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