化合物问答
(2S)-4-[[1-(4,4-二甲基-2,6-二氧代环己亚基)乙基]氨基]-2-[[(9H-芴-9-基甲氧基)羰基]氨基]丁酸(CAS号：235788-61-1)通常如何合成？
答案
![(2S)-4-{[2-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]amino}-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}butanoic acid](https://cnstatic.chemtradehub.com/structs/235/235788-61-1-21ab.webp "(2S)-4-{[2-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]amino}-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}butanoic acid")
(2S)-4-[[1-(4,4-二甲基-2,6-二氧代环己亚基)乙基]氨基]-2-[[(9H-芴-9-基甲氧基)羰基]氨基]丁酸通常通过合成芴酮衍生物与相应的胺反应制备。合成过程中，使用硫酸或磷酸作为催化剂，选择性好，产率较高。常用的合成路线包括芴酮的保护、胺的引入以及最终酰胺的形成。
关于
CAS号
235788-61-1
英文名称
(2S)-4-{[2-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]amino}-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}butanoic acid
中文名称
(2S)-4-[[1-(4,4-二甲基-2,6-二氧代环己亚基)乙基]氨基]-2-[[(9H-芴-9-基甲氧基)羰基]氨基]丁酸
分子式
C29H32N2O6
分子量
504.58 g/mol
SMILES
CC(=NCCC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13)C4=C(CC(CC4=O)(C)C)O
InChIKey
NFCIJFBWDXNMRV-DEOSSOPVSA-N
最后更新: 2025-10-26 09:39
![(2S)-4-{[2-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]amino}-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}butanoic acid — 江西探真生物技术有限公司](https://cnstatic.chemtradehub.com/suppliers/67cddec957537e5c8069ae69/67cddec957537e5c8069ae69-logo.webp){kind=logo}
![(2S)-4-{[2-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]amino}-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}butanoic acid — 金锦乐（湖南）化学有限公司](https://cnstatic.chemtradehub.com/suppliers/67ce76192b2de6e8e95a464e/67ce76192b2de6e8e95a464e-logo.webp){kind=logo}
![(2S)-4-{[2-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]amino}-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}butanoic acid — 乐研试剂](https://cnstatic.chemtradehub.com/suppliers/67ce1f8657537e5c8069b370/67ce1f8657537e5c8069b370-logo.webp){kind=logo}