化合物问答
头孢拉宗(CAS号：76610-84-9)通常如何合成？
答案
![(6R,7S)-7-({N-[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]-D-threonyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid](https://cnstatic.chemtradehub.com/structs/766/76610-84-9-cd54.webp "(6R,7S)-7-({N-[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]-D-threonyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid")
头孢拉宗的合成通常通过多步反应完成，包括酰化、环化、还原等步骤。首先，从头孢烷酸出发，通过酰化反应引入D-四氢噻吩环，随后进行环合反应形成头孢拉宗的骨架结构，最后通过还原和保护基团的脱除等步骤获得目标化合物。常用的催化剂包括金属钯和氢气。
关于
CAS号
76610-84-9
英文名称
(6R,7S)-7-({N-[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]-D-threonyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
中文名称
头孢拉宗
分子式
C22H29N9O9S2
分子量
342.25 g/mol
SMILES
CCN1CCN(C(=O)C1=O)C(=O)NC(C(C)O)C(=O)NC2(C3N(C2=O)C(=C(CS3)CSC4=NN=NN4C)C(=O)O)OC
InChIKey
SMSRCGPDNDCXFR-CYWZMYCQSA-N
最后更新: 2025-11-01 22:12
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![(6R,7S)-7-({N-[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]-D-threonyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid — 深圳爱拓化学有限公司](https://cnstatic.chemtradehub.com/suppliers/67ced0fb2b2de6e8e95a67fa/67ced0fb2b2de6e8e95a67fa-logo.webp){kind=logo}