化合物问答
Vorapaxar(CAS号：900161-12-8)通常如何合成？
答案
![Ethyl ((1R,3aR,4aR,6R,8aR,9S,9aS)-9-(diphenylcarbamoyl)-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl)carbamate](https://cnstatic.chemtradehub.com/structs/900/900161-12-8-44e4.webp "Ethyl ((1R,3aR,4aR,6R,8aR,9S,9aS)-9-(diphenylcarbamoyl)-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl)carbamate")
Vorapaxar通常通过多步合成得到。首先，通过多环化合物的构建和修饰，得到中间体，然后与苯基碳酰胺反应得到目标化合物。合成过程中使用催化剂提高反应选择性和产率，但具体催化剂种类未公开。
关于
CAS号
900161-12-8
英文名称
Ethyl ((1R,3aR,4aR,6R,8aR,9S,9aS)-9-(diphenylcarbamoyl)-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl)carbamate
中文名称
Vorapaxar
分子式
C29H34N2O5
分子量
490.6 g/mol
SMILES
CCOC(=O)NC1CCC2C(C1)CC3C(C2C(=O)N(C4=CC=CC=C4)C5=CC=CC=C5)C(OC3=O)C
InChIKey
QIHOOQHZKUMXOB-RBNACLDASA-N
最后更新: 2025-11-08 00:00
![Ethyl ((1R,3aR,4aR,6R,8aR,9S,9aS)-9-(diphenylcarbamoyl)-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl)carbamate — 上海源叶生物科技有限公司](https://cnstatic.chemtradehub.com/suppliers/67ce9f132b2de6e8e95a48fe/67ce9f132b2de6e8e95a48fe-logo.webp){kind=logo}
![Ethyl ((1R,3aR,4aR,6R,8aR,9S,9aS)-9-(diphenylcarbamoyl)-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl)carbamate — 湖北诺纳科技有限公司](https://cnstatic.chemtradehub.com/suppliers/67ce946e2b2de6e8e95a4840/67ce946e2b2de6e8e95a4840-logo.webp){kind=logo}