化合物问答
N,N'-(1R,2R)-1,2-环己二基双[N'-[3,5-双(三氟甲基)苯基]硫脲(CAS号：743458-79-9)通常如何合成？
答案
![N,N'-(1R,2R)-1,2-Cyclohexanediylbis[N'-[3,5-bis(trifluoromethyl)phenyl]thiourea](https://cnstatic.chemtradehub.com/structs/743/743458-79-9-eead.webp "N,N'-(1R,2R)-1,2-Cyclohexanediylbis[N'-[3,5-bis(trifluoromethyl)phenyl]thiourea")
该化合物通常通过将1,2-环己二胺与3,5-双(三氟甲基)苯磺酰氯反应，随后用硫脲进行处理而制备。该合成过程通常在惰性气体保护下进行，使用无水有机溶剂。反应产率约为75%-85%，并可以根据需要选择适当的催化剂以提高选择性和产率。
关于
CAS号
743458-79-9
英文名称
N,N'-(1R,2R)-1,2-Cyclohexanediylbis[N'-[3,5-bis(trifluoromethyl)phenyl]thiourea
中文名称
N,N'-(1R,2R)-1,2-环己二基双[N'-[3,5-双(三氟甲基)苯基]硫脲
分子式
C24H20F12N4S2
分子量
656.56 g/mol
SMILES
S=C(Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F)N[C@@H]1CCCC[C@H]1NC(=S)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F
InChIKey
VALSAKIMMYEMHC-QZTJIDSGSA-N
最后更新: 2025-12-26 02:37
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