化合物问答
4-(4-{4-[4-氟-3-(三氟甲基)苯基]-1-甲基-1H-咪唑-2-基}-1-哌啶基)-1H-吡唑[3,4-d]嘧啶-4-甲苯磺酸盐(1:1)(CAS号：1082949-68-5)通常如何合成？
答案
![4-(4-{4-[4-Fluoro-3-(trifluoromethyl)phenyl]-1-methyl-1H-imidazol-2-yl}-1-piperidinyl)-1H-pyrazolo[3,4-d]pyrimidine 4-methylbenzenesulfonate (1:1)](https://cnstatic.chemtradehub.com/structs/108/1082949-68-5-00b6.webp "4-(4-{4-[4-Fluoro-3-(trifluoromethyl)phenyl]-1-methyl-1H-imidazol-2-yl}-1-piperidinyl)-1H-pyrazolo[3,4-d]pyrimidine 4-methylbenzenesulfonate (1:1)")
该化合物通常通过将4-甲苯磺酸盐与4-哌啶基-1H-吡唑[3,4-d]嘧啶-4-甲酸衍生物在高温下反应合成。反应过程中需要使用催化剂，例如三乙胺，反应产率大约在70%-80%之间。
关于
CAS号
1082949-68-5
英文名称
4-(4-{4-[4-Fluoro-3-(trifluoromethyl)phenyl]-1-methyl-1H-imidazol-2-yl}-1-piperidinyl)-1H-pyrazolo[3,4-d]pyrimidine 4-methylbenzenesulfonate (1:1)
分子式
C28H27F4N7O3S
分子量
617.6290000000002 g/mol
SMILES
Cn1cc(nc1C1CCN(CC1)c1ncnc2c1cn[nH]2)c1ccc(c(c1)C(F)(F)F)F.Cc1ccc(cc1)S(=O)(=O)O
InChIKey
HDYUXDNMHBQKAU-UHFFFAOYSA-N
最后更新: 2025-12-26 02:37
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