化合物问答
他唑巴坦(CAS号：80353-26-0)通常如何合成？
答案
![Diphenylmethyl (2S,5R,6S)-6-bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4-oxide](https://cnstatic.chemtradehub.com/structs/803/80353-26-0-ca3f.webp "Diphenylmethyl (2S,5R,6S)-6-bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4-oxide")
他唑巴坦通常通过缩合反应合成，使用氯乙酰氯和2-氨基-3-（2,4-二氯苯基）丙酸甲酯为原料，在碱性条件下进行反应，生成相应的产物。通过合适的后处理步骤，可以得到目标化合物。
关于
CAS号
80353-26-0
英文名称
Diphenylmethyl (2S,5R,6S)-6-bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4-oxide
中文名称
他唑巴坦
分子式
C21H20BrNO4S
分子量
462.37 g/mol
SMILES
CC1(C(N2C(S1=O)C(C2=O)Br)C(=O)OC(C3=CC=CC=C3)C4=CC=CC=C4)C
InChIKey
MHQYJIDSSLKVOK-OCZDZXRVSA-N
最后更新: 2025-12-28 14:56
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