化合物问答
Cetirizine EP Impurity B DiHCl(CAS号：1000690-91-4)通常如何合成？
答案
![{4-[(4-Chlorophenyl)(phenyl)methyl]-1-piperazinyl}acetic acid dihydrochloride](https://cnstatic.chemtradehub.com/structs/100/1000690-91-4-391b.webp "{4-[(4-Chlorophenyl)(phenyl)methyl]-1-piperazinyl}acetic acid dihydrochloride")
Cetirizine EP Impurity B DiHCl通常通过一锅法合成，首先将4-氯苯基-苯甲基氯甲酸酯与1-哌嗪乙酸反应，生成相应的酸，然后与盐酸反应得到二盐酸盐。该合成方法具有良好的选择性和较高的产率。
关于
CAS号
1000690-91-4
英文名称
{4-[(4-Chlorophenyl)(phenyl)methyl]-1-piperazinyl}acetic acid dihydrochloride
中文名称
Cetirizine EP Impurity B DiHCl
分子式
C19H23Cl3N2O2
分子量
417.76 g/mol
SMILES
c1ccc(cc1)C(c2ccc(cc2)Cl)N3CCN(CC3)CC(=O)O.Cl.Cl
InChIKey
LSPZEDLYSAUAQV-UHFFFAOYSA-N
最后更新: 2025-12-31 06:49
![查看上海绩祥生物科技有限公司的{4-[(4-Chlorophenyl)(phenyl)methyl]-1-piperazinyl}acetic acid dihydrochloride](https://cnstatic.chemtradehub.com/suppliers/67ce6f4d2b2de6e8e95a45bf/67ce6f4d2b2de6e8e95a45bf-logo.webp){kind=logo}
![查看上海源叶生物科技有限公司的{4-[(4-Chlorophenyl)(phenyl)methyl]-1-piperazinyl}acetic acid dihydrochloride](https://cnstatic.chemtradehub.com/suppliers/67ce9f132b2de6e8e95a48fe/67ce9f132b2de6e8e95a48fe-logo.webp){kind=logo}