化合物问答
噻奈普汀乙酯(CAS号：66981-77-9)通常如何合成？
答案
![Ethyl 7-[(3-chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoate](https://cnstatic.chemtradehub.com/structs/669/66981-77-9-6562.webp "Ethyl 7-[(3-chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoate")
噻奈普汀乙酯通常通过先合成噻奈普汀母核，再与乙酸乙酯进行酯化反应得到。具体合成步骤包括：将3-氯-6-甲基-5,5-二氧代-6,11-二氢二苯并[c,f][1,2]噻唑哌啶与适当的酰化剂反应生成中间体，然后与乙酸乙酯在酸性或碱性条件下进行酯化反应，最终得到噻奈普汀乙酯。
关于
CAS号
66981-77-9
英文名称
Ethyl 7-[(3-chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoate
中文名称
噻奈普汀乙酯
分子式
C23H29ClN2O4S
分子量
465.01500000000016 g/mol
SMILES
CCOC(=O)CCCCCCNC1c2ccccc2N(S(=O)(=O)c3c1ccc(c3)Cl)C
InChIKey
FEFUFMZSNHPQDX-UHFFFAOYSA-N
最后更新: 2025-12-31 11:48
![查看上海绩祥生物科技有限公司的Ethyl 7-[(3-chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoate](https://cnstatic.chemtradehub.com/suppliers/67ce6f4d2b2de6e8e95a45bf/67ce6f4d2b2de6e8e95a45bf-logo.webp){kind=logo}
![查看上海源叶生物科技有限公司的Ethyl 7-[(3-chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoate](https://cnstatic.chemtradehub.com/suppliers/67ce9f132b2de6e8e95a48fe/67ce9f132b2de6e8e95a48fe-logo.webp){kind=logo}
![查看深圳振强生物技术有限公司的Ethyl 7-[(3-chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoate](https://cnstatic.chemtradehub.com/suppliers/67cec9142b2de6e8e95a51e7/67cec9142b2de6e8e95a51e7-logo.webp){kind=logo}
![查看湖北扬信医药科技有限公司的Ethyl 7-[(3-chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoate](https://cnstatic.chemtradehub.com/suppliers/67cded3957537e5c8069af88/67cded3957537e5c8069af88-logo.webp){kind=logo}
![查看山东诚创蓝海医药科技有限公司的Ethyl 7-[(3-chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoate](https://cnstatic.chemtradehub.com/suppliers/67ce78212b2de6e8e95a467d/67ce78212b2de6e8e95a467d-logo.webp){kind=logo}