化合物问答
吲哚乙酸-13c6(CAS号：1058653-74-9)通常如何合成？
答案
![5-[5-(Chloroacetyl)-2-ethoxyphenyl]-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one](https://cnstatic.chemtradehub.com/structs/105/1058653-74-9-ce03.webp "5-[5-(Chloroacetyl)-2-ethoxyphenyl]-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one")
吲哚乙酸-13c6通常通过多步合成方法制备，首先合成中间体5-氯乙酰基-2-乙氧基苯基甲醇，然后与1-甲基-3-丙基-1,6-二氢-7H-吡唑[4,3-d]嘧啶-7-酮反应得到目标化合物。合成过程中常用催化剂为三乙胺等碱性物质，产率约为70%-80%。
关于
CAS号
1058653-74-9
英文名称
5-[5-(Chloroacetyl)-2-ethoxyphenyl]-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
中文名称
吲哚乙酸-13c6
分子式
C19H21ClN4O3
分子量
388.86 g/mol
SMILES
CCCc1nn(c2c1[nH]c(nc2=O)c1cc(ccc1OCC)C(=O)CCl)C
InChIKey
UOJGGFDIPKRVTP-UHFFFAOYSA-N
最后更新: 2026-01-02 00:31
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