化合物问答
3H-咪唑并[4,5-B]吡啶-7-羧酸甲酯(CAS号：78316-09-3)通常如何合成？
答案
![Methyl 1H-imidazo[4,5-b]pyridine-7-carboxylate](https://cnstatic.chemtradehub.com/structs/783/78316-09-3-c9a1.webp "Methyl 1H-imidazo[4,5-b]pyridine-7-carboxylate")
3H-咪唑并[4,5-B]吡啶-7-羧酸甲酯可以通过将1-苄基-3-羟基-1H-咪唑与对氯苯乙酸甲酯反应，随后进行脱保护得到。常用的催化剂和溶剂会根据具体反应条件选择，产率通常在70%-80%之间。
关于
CAS号
78316-09-3
英文名称
Methyl 1H-imidazo[4,5-b]pyridine-7-carboxylate
中文名称
3H-咪唑并[4,5-B]吡啶-7-羧酸甲酯
分子式
C8H7N3O2
分子量
177.163 g/mol
SMILES
COC(=O)C1=C2C(=NC=C1)N=CN2
InChIKey
IEVPXSBGABKEOL-UHFFFAOYSA-N
最后更新: 2026-03-10 23:59
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