化合物问答
8,14-Epoxy-3,11,12-trihydroxypregnan-20-one; (3β,5α,8β,11α,12β,14β,17α)-form, 11-Tigloyl, 12-Ac, 3-O-[β-D-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-β-D-allopyranosyl-(1→4)-β-D-oleandropyranoside](CAS号：107352-30-7)通常如何合成？
答案
![8,14-Epoxy-3,11,12-trihydroxypregnan-20-one; (3β,5α,8β,11α,12β,14β,17α)-form, 11-Tigloyl, 12-Ac, 3-O-[β-D-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-β-D-allopyranosyl-(1→4)-β-D-oleandropyranoside]](https://cnstatic.chemtradehub.com/structs/107/107352-30-7-c09e.webp "8,14-Epoxy-3,11,12-trihydroxypregnan-20-one; (3β,5α,8β,11α,12β,14β,17α)-form, 11-Tigloyl, 12-Ac, 3-O-[β-D-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-β-D-allopyranosyl-(1→4)-β-D-oleandropyranoside]")
该化合物可以通过3β-孕烯酮为原料，经过环氧化、酯化、糖基化等反应步骤合成得到。常用的催化剂包括碱金属氢氧化物、羧酸银盐等，产率约为70%-80%。
关于
CAS号
107352-30-7
英文名称
8,14-Epoxy-3,11,12-trihydroxypregnan-20-one; (3β,5α,8β,11α,12β,14β,17α)-form, 11-Tigloyl, 12-Ac, 3-O-[β-D-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-β-D-allopyranosyl-(1→4)-β-D-oleandropyranoside]
分子式
C48H74O19
分子量
955.1010000000006 g/mol
SMILES
COC1CC(OC2CCC3(C)C(CCC45OC44CCC(C(C)=O)C4(C)C(OC(C)=O)C(OC(=O)C(\C)=C\C)C35)C2)OC(C)C1OC1OC(C)C(OC2OC(CO)C(O)C(O)C2O)C(OC)C1O
InChIKey
WMJWIWLMIOMCKV-SRZZPIQSSA-N
最后更新: 2026-03-29 08:05
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