N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]adenosine（CAS号：104992-55-4）

N-苯甲酰基-5'-O-(4,4-二甲氧基三苯甲基)-2'-O-[(叔丁基)二甲基硅基]腺苷-3'-(2-氰基乙基-N,N-二异丙基)亚磷酰胺

基本信息

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CAS号

104992-55-4

分子式

C53H66N7O8PSi

分子量

17.03 g/mol

化学分类

基础化工原料有机化学品羧酸类

基础化工原料有机化学品醚类

基础化工原料有机化学品腈类

基础化工原料有机化学品杂环化合物

医药化工医药中间体杂环中间体

精细化工产品染料和颜料有机染料

精细化工产品表面活性剂阴离子表面活性剂

农用化学品农药杀虫剂

实验室化学品科研化学品生化试剂

基本物理性质

SMILES

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CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1O[Si](C)(C)C(C)(C)C)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC

InChI

InChI=1S/C53H66N7O8PSi/c1-36(2)60(37(3)4)69(65-32-18-31-54)67-46-44(33-64-53(39-21-16-13-17-22-39,40-23-27-42(62-8)28-24-40)41-25-29-43(63-9)30-26-41)66-51(47(46)68-70(10,11)52(5,6)7)59-35-57-45-48(55-34-56-49(45)59)58-50(61)38-19-14-12-15-20-38/h12-17,19-30,34-37,44,46-47,51H,18,32-33H2,1-11H3,(H,55,56,58,61)/t44-,46-,47-,51-,69?/m1/s1

InChIKey

FFXHNCNNHASXCT-RFMFGJHUSA-N

LogP

0.16199999999999998

拓扑极性表面积

35.0 Å²

氢键供体/受体

3 / 1

复杂度

1630

安全信息

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危险说明

H302 吞咽有害
急性毒性-经口

H315 造成皮肤刺激
皮肤腐蚀/刺激

H319 造成严重眼刺激
严重眼损伤/眼刺激

H332 吸入有害
急性毒性-吸入

H335 可能造成呼吸道刺激
特定目标器官毒性-单次接触；呼吸道刺激

同义词与引用数据

英文

5'-O-(4,4'-Dimethoxy)-N6-benzoyl-adenosine-2'-O-[(1,1-dimethylethyl)dimethylsilyl-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramid ite
DMT-2'O-TBDMS-rA(bz) Phosphoramidite, configured for MerMade
DMT-2'O-TBDMS-rA(bz) amidite
AKOS015999120
PD158240
1803193-36-3
SCHEMBL667192
Bz-rA Phosphoramidite
HY-W006102
104992-55-4
DMT-2'O-TBDMS-rA(bz) Pharmadite(R)
Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
Bz-rAPhosphoramidite
N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]purin-6-yl]benzamide
CS-W006102
DMT-2'O-TBDMS-rA(bz) Phosphoramidite, configured for ABI
C53H66N7O8PSi
(2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
AC-32371
DTXSID40463231
DMT-2'O-TBDMS-rA(bz) Phosphoramidite, configured for ??KTA(R) and OligoPilot(R)
MFCD00080297
N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 3'-CE phosphoramidite
J-700105
5'-O-DMT-2'-O-tert-Butyldimethylsiyl-N6-Benzoyl-adenosine 3'-CE phosphoramidite
DMT-2'O-TBDMS-Ra(Bz) Phosphoramidite
N-Benzoyl-5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]adenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
DMT-2'O-TBDMS-rA(bz) Phosphoramidite, configured for (??KTA(R) and OligoPilot(R))
5'-O-DMT-2'-TBDMS-rA(N-Bz)-3'-CEDPA
2'-TBDMS -Bz-rA-CE-Phosphoramidite
Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI)