6-O-Methyl-2',4''-bis-O-(trimethylsilyl)-9-[O-(1-ethoxy-1-methylethyl)oxime]-Erythromycin（CAS号：119665-62-2）

硅醚保护产物:甲氧基-M3

基本信息

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CAS号

119665-62-2

分子式

C49H96N2O14Si2

分子量

993.48 g/mol

化学分类

基础化工原料有机化学品羧酸类

基础化工原料有机化学品酯类

基础化工原料有机化学品醚类

基础化工原料有机化学品杂环化合物

医药化工医药中间体杂环中间体

精细化工产品表面活性剂阴离子表面活性剂

聚合物和塑料热塑性塑料聚烯烃

实验室化学品科研化学品生化试剂

基本物理性质

沸点

838.422 °C at 760 mmHg

闪点

460.861 °C

折射率

1.499

SMILES

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CCC1C(C(C(C(=NOC(C)(C)OCC)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O[Si](C)(C)C)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O[Si](C)(C)C)(C)OC)C)C)O)(C)O

InChI

InChI=1S/C49H96N2O14Si2/c1-24-36-49(13,54)41(52)31(5)38(50-65-46(9,10)57-25-2)29(3)27-47(11,55-16)42(62-45-40(63-66(18,19)20)35(51(14)15)26-30(4)58-45)32(6)39(33(7)44(53)60-36)61-37-28-48(12,56-17)43(34(8)59-37)64-67(21,22)23/h29-37,39-43,45,52,54H,24-28H2,1-23H3/b50-38+/t29-,30-,31+,32+,33-,34+,35+,36-,37+,39+,40-,41-,42-,43+,45+,47-,48-,49-/m1/s1

InChIKey

SFTHBPKNOPSKEE-CATVDQELSA-N

LogP

7.734200000000012

拓扑极性表面积

174.66 Å²

氢键供体/受体

2 / 16

复杂度

1600

同义词与引用数据

英文

6-O-Methyl-2',4''-bis-O-(trimethylsilyl)-9-[O-(1-ethoxy-1-methylethyl)oxime]-Erythromycin
IntermediateofClarithromycin
AKOS015920282
DS-1405
(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-6-methyl-3-[(trimethylsilyl)oxy]oxan-2-yl]oxy}-10-{[(2-ethoxypropan-2-yl)oxy]imino}-14-ethyl-12,13-dihydroxy-7-methoxy-4-{[(2R,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-[(trimethylsilyl)oxy]oxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one
DTXSID70680611
6-O-Methyl-2',4''-bis-O-(trimethylsilyl)erythromycin-9-[O-(1-ethoxy-1-methylethyl)oxime]
Erythromycin, 6-O-methyl-2',4''-bis-O-(trimethylsilyl)-, 9-[O-(1-ethoxy-1-methylethyl)oxime]
PUBCHEM_52915086
119665-62-2
(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-6-methyl-3-trimethylsilyloxyoxan-2-yl]oxy-10-(2-ethoxypropan-2-yloxyimino)-14-ethyl-12,13-dihydroxy-7-methoxy-4-[(2R,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-trimethylsilyloxyoxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one
Erythromycin,6-O-methyl-2',4''-bis-O-(trimethylsilyl)-,9-[o-(1-ethoxy-1-methylethyl)oxime]
Intermediate of Clarithromycin
Erythromycin,6-O-methyl-2',4''-bis-O-(trimethylsilyl)-,9-[O-(1-ethoxy-1-methylethyl)oxime
Erythromycin,6-O-methyl-2',4''-bis-O-(trimethylsilyl)-, 9-[O-(1-ethoxy-1-methylethyl)oxime]
6-O-Methyl-2',4''-bis-O-(trimethylsilyl)-9-[O-(1-ethoxy-1-methylethyl)oxime]
6-O-Methyl-2',4''-bis-O-(trimethylsilyl)erythromycin- 9-[O-(1-ethoxy-1-methylethyl)oxime]
6-O-Methyl-2',4''-bis-O-(trimethylsilyl)erythromycin 9-[O-(1-ethoxy-1-methylethyl)oxime]
9-[O-(1-ethoxy-1- methylethy) oxime
Erythromycin,6-O-methyl-2`,4``-bis-O-(trimethylsilyl),9-[O-(1-ethoxy-1-methylethyl) oxime
(3R,4S,5S,6R,7R,9R,11S,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-6-methyl-3-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-10-(((2-ethoxypropan-2-yl)oxy)imino)-14-ethyl-12,13-dihydroxy-7-methoxy-4-(((2R,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-((trimethylsilyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one