(1R,2R,3S,4R,6S)-4,6-Diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside sulfate (1:1)（CAS号：1405-10-3）

硫酸新霉素

基本信息

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CAS号

1405-10-3

分子式

C23H48N6O17S

分子量

712.73 g/mol

化学分类

基础化工原料有机化学品羧酸类

基础化工原料有机化学品醚类

基础化工原料有机化学品胺类

基础化工原料有机化学品杂环化合物

医药化工医药中间体杂环中间体

精细化工产品表面活性剂阴离子表面活性剂

聚合物和塑料热塑性塑料聚烯烃

实验室化学品科研化学品生化试剂

基本物理性质

熔点

>360°C

沸点

1046.1°C at 760 mmHg

水溶性

Soluble in water

闪点

56℃

溶解度

H2O: 50 mg/mL As a stock solution. Stock solutions should be filter sterilized and stored at 2-8°C. Stable at 37°C for 5 days.

折射率

56 ° (C=10, H2O)

比旋光度

+53° ~ +59° (c=10, H2O)

SMILES

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C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)N)OC3C(C(C(O3)CO)OC4C(C(C(C(O4)CN)O)O)N)O)O)N.OS(=O)(=O)O

InChI

InChI=1S/C23H46N6O13.H2O4S/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22;1-5(2,3)4/h5-23,30-36H,1-4,24-29H2;(H2,1,2,3,4)/t5-,6+,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+;/m1./s1

InChIKey

OIXVKQDWLFHVGR-WQDIDPJDSA-N

LogP

-9.548100000000018

拓扑极性表面积

427.71 Å²

氢键供体/受体

21 / 23

复杂度

953

安全信息

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GHS危险象形图

H317

H334

危险说明

H317 可能导致皮肤过敏反应
致敏性-皮肤

H334 吸入可能导致过敏或哮喘症状或呼吸困难
致敏性-呼吸

同义词与引用数据

英文

SCHEMBL373681
D-Streptamine, O-2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl-(1-3)-O-beta-D-ribofuranosyl-(1-5)-O-(2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl-(1-4))-2-deoxy-, sulfate (salt)
Isofra (TN)
CHEBI:53636
OIXVKQDWLFHVGR-WQDIDPJDSA-N
HMS2095O18
MFCD00150827
Fradiomycin sulfate
Neomycin sulphate, Antibiotic for Culture Media Use Only
Neomycin B sulfate
(2S,3S,4R,5R,6R)-5-Amino-2-(aminomethyl)-6-(((2R,3S,4R,5S)-5-(((1R,2R,3S,5R,6S)-3,5-diamino-2-(((2R,3R,4R,5S,6R)-3-amino-6-(aminomethyl)-4,5-dihydroxytetrahydro-2H-pyran-2-yl)oxy)-6-hydroxycyclohexyl)oxy)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl)oxy)tetrahydro-2H-pyran-3,4-diol xsulfate
(1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside sulfate
EINECS 248-770-9
Neomycin Sulfate hydrate
KS-1358
F0649
Neoamine,(S)
NEOMYCIN SULFATE
1405-10-3
AKOS016340327
Neomycin B sulphate
Framycetin sulphate
WHO Third International Standard for Neomycin
D07994
Framycetin sulfate
Neomycin sulfate, USP grade
Neomycin sulfate for microbiological assay
Neomycin Trisulfate Hydrate
1404-04-2 (acid)
28002-70-2
Neomycin Sulphate B