Emtricitabine Menthyl Ester（CAS号：147126-75-8）

5-(4-氨基-5-氟-2-氧代-1(2H)-嘧啶)-1,3-氧硫杂环戊烷-2-甲酸 5-甲基-2-异丙基环己醇酯

基本信息

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CAS号

147126-75-8

分子式

C18H26FN3O4S

分子量

399.5 g/mol

化学分类

基础化工原料有机化学品羧酸类

基础化工原料有机化学品酯类

基础化工原料有机化学品醚类

基础化工原料有机化学品胺类

基础化工原料有机化学品杂环化合物

医药化工医药中间体杂环中间体

精细化工产品染料和颜料有机染料

精细化工产品表面活性剂阴离子表面活性剂

精细化工产品专用化学品紫外线稳定剂

农用化学品农药除草剂

基本物理性质

沸点

519.2°C at 760 mmHg

SMILES

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CC1CCC(C(C1)OC(=O)C2OC(CS2)N3C=C(C(=NC3=O)N)F)C(C)C

InChI

InChI=1S/C18H26FN3O4S/c1-9(2)11-5-4-10(3)6-13(11)25-16(23)17-26-14(8-27-17)22-7-12(19)15(20)21-18(22)24/h7,9-11,13-14,17H,4-6,8H2,1-3H3,(H2,20,21,24)

InChIKey

AUTCQXVTOIJYOT-UHFFFAOYSA-N

LogP

3.13790

复杂度

669

安全信息

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危险说明

H302 吞咽有害
急性毒性-经口

H315 造成皮肤刺激
皮肤腐蚀/刺激

H319 造成严重眼刺激
严重眼损伤/眼刺激

H332 吸入有害
急性毒性-吸入

H335 可能造成呼吸道刺激
特定目标器官毒性-单次接触；呼吸道刺激

同义词与引用数据

英文

AC-24576
5-Methyl-2-(propan-2-yl)cyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
2-Isopropyl-5-methylcyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
764659-79-2
5-Fluoro ent-Lamivudine Acid D-Menthol Ester;(5S)-(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
(2S,5R)-5-Fluoro cytosine-1-yl-[1,3]-oxathiolane-2-carboxylic acid menthyl ester(FCME)
(5-methyl-2-propan-2-ylcyclohexyl) 5-(4-amino-5-fluoro-2-oxopyrimidin-1-yl)-1,3-oxathiolane-2-carboxylate
(2S,5R)-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
DTXSID60694828
(2S,5R)-(1S,2R,5S)-2-Isopropyl-5-methylcyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
147126-75-8
SCHEMBL2319744
[1R-[1(2S*,5R*),2beta,5alpha]]-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester
5-(4-AMINO-5-FLUORO-2-OXO-1(2H)-PYRIMIDINYL)-1,3-OXATHIOLANE-2-CARBOXYLIC ACID 5-METHYL-2-(1-METHYLETHYL)CYCLOHEXYL ESTER
[1R-[1(2S*,5R*),2beta,5alpha]]-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carbox
SB48778
AKOS025293894
AS-17614
BCP10738
FCME
5-(4-amino-5-fluoro-2-oxo-1(2h)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester
[1r-[1(2s*,5r*),2beta,5alpha]]-5-(4-amino-5-fluoro-2-oxo-1(2h)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester
(2S,5R)-5-Fluoro cytosine-1-yl-[1,3]-oxathiolane-2-carboxylic acid menthyl ester (FCME)
(2S,5R)-5-Fluoro cytosine-1-yl-[1,3]-oxathiolane-2-carboxylic acid menthyl ester
(2S,5R)-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carbox...
V0970
The intermediate of his bin
EMtricitabine InterMediate- FCME
[1R-[1(2S*,5R*),2beta,5alpha]]-5-(4-AMino-5-fluoro-2-oxo-1(2H)-
(1R,2S,5R)-MENTHYL-5(S)-FLUOROCYTOSINE-1-YL-[1,3]-OXATHIOLANE-2R-CARBOXYLATE
(2S,5R)-5-Fluoro cytosine-1-yl-[1,3]-oxathiolane-2-carboxylic acid methyl ester

中文

5-(4-氨基-5-氟-2-氧代-1(2H)-嘧啶)-1,3-氧硫杂环戊烷-2-甲酸 5-甲基-2-异丙基环己醇酯
(2S,5R)-5-氟胞嘧啶-1-基-[1,3]-氧硫杂环戊烷-2-羧酸孟酯
(2S,5R)-5-氟胞嘧啶-1-基-[1,3]-氧硫杂环戊烷-2-羧酸孟酯(FCME)
(2R,5R)-5-氟胞嘧啶-1-基-[1,3]-
(2S,5R)-5-氟胞嘧啶-1-基-[1,3]-
5-(4-氨基-5-氟-2-氧代-1(2H)-嘧啶)-1,3-氧硫杂环戊烷-2-甲酸-5-甲基-2-异丙基环己醇酯
5S-（5-氟胞嘧啶）-1,3-氧硫杂环戊烷-2R-甲酸薄荷醇酯 (FCME)
恩曲他滨中间体 F-CME
甲烷磺酸(2-二环己基膦基-2'',4'',6''-三异丙基-1,1''-联苯基)(2''-氨基-1,1''-联苯-2-基)钯(II)
甲烷磺酸(2-二环己基膦基-2,4,6-三异丙基-1,1-联苯基)(2-氨基-1,1-联苯-2-基)钯(II)
(2S,5R)-(1R,2S,5R)-5-(4-氨基-5-氟-2-氧代-1(2H)-嘧啶)-1,3-氧硫杂环戊烷-2-甲酸5-甲基-2-异丙基环己醇酯
(2S,5R)-5-氟胞嘧啶-1-基-[1,3]-氧硫杂环戊烷
(2S,5R)-5-氟胞嘧啶-1-基-1,3-氧硫杂环戊烷-2-羧酸孟酯(FCM
(2S,5R)-5-氟胞嘧啶-1-基-(1,3)-氧硫杂环戊烷-2-羧酸孟酯(FCME)
(2R,5S)-5-氟胞嘧啶-1-基-[1,3]-氧硫杂环戊烷-2-羧酸孟酯(FCME)
5-(4-氨基-5-氟-2-氧代-1(2H)-嘧啶)-1,3-氧硫杂环戊烷-2-甲酸 5-甲基-2-异丙基环己醇酯 FCME
5-(4-氨基-5-氟-2-氧代-1(2H)-嘧啶-1,3-氧硫杂环戊烷-2-甲酸-5-甲基-2-异丙基环已醇酯(FCME)
恩曲他滨中间体 F-CME (2S,5R)-5-FLUORO CYTOSINE-1-YL-[1,3]-OXATHIOLANE-2-CARBOXYLIC ACID MENTHYL ESTER