Clindamycin HCl (Clindamycin Phosphate EP Impurity E HCl)（CAS号：21462-39-5）

盐酸克林霉素

基本信息

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CAS号

21462-39-5

分子式

C18H34Cl2N2O5S

分子量

461.45 g/mol

化学分类

基础化工原料有机化学品羧酸类

基础化工原料有机化学品醚类

基础化工原料有机化学品杂环化合物

医药化工医药中间体杂环中间体

精细化工产品表面活性剂阴离子表面活性剂

实验室化学品科研化学品生化试剂

基本物理性质

熔点

141 ºC

沸点

628.1°C at 760 mmHg

闪点

345.1 °C

溶解度

H2O: 50 mg/mL, clear, colorless

折射率

143 ° (C=2, H2O)

比旋光度

+142.0° - +151.0° (c=2, H2O)

SMILES

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CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)Cl.Cl

InChI

InChI=1S/C18H33ClN2O5S.ClH/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4;/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25);1H/t9-,10+,11-,12+,13-,14+,15+,16+,18+;/m0./s1

InChIKey

AUODDLQVRAJAJM-XJQDNNTCSA-N

LogP

0.8113000000000001

拓扑极性表面积

102.26000000000002 Å²

氢键供体/受体

4 / 7

复杂度

502

安全信息

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危险说明

H302 吞咽有害
急性毒性-经口

H315 造成皮肤刺激
皮肤腐蚀/刺激

H319 造成严重眼刺激
严重眼损伤/眼刺激

H335 可能造成呼吸道刺激
特定目标器官毒性-单次接触；呼吸道刺激

同义词与引用数据

英文

UNII-T20OQ1YN1W
Clindamycin hydrochloride monohydrate
NSC-756696
CLINDAMYCIN HYDROCHLORIDE [MI]
U 21251F
Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside monohydrochloride
AMY33461
NS00076311
Clindamycin hydrochloride, lincosamide antibiotic
21462-39-5
Clindamycin hydrochloride (JP17/USP)
CLINDAMYCIN HYDROCHLORIDE [USP MONOGRAPH]
Clindamycin hydrochloride (USP:BAN:JAN)
L-THREO-.ALPHA.-D-GALACTO-OCTOPYRANOSIDE, METHYL 7-CHLORO-6,7,8-TRIDEOXY-6-(((1-METHYL-4-PROPYL-2-PYRROLIDINYL)CARBONYL)AMINO)-1-THIO-,(2S-TRANS)-, MONOHYDROCHLORIDE
Clindamycin hydrochloride
CLINDAMYCIN HYDROCHLORIDE [MART.]
(2S,4R)-N-[(1S,2S)-2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide;hydrochloride
NSC 756696
(4R)-N-[(1S,2S)-2-chloro-1-[(3R,4R,6R)-3,4,5-trihydroxy-6-methylsulfanyl-tetrahydropyran-2-yl]propyl]-1-methyl-4-propyl-pyrrolidine-2-carboxamide hydrochloride;Clindamycin hydrochloride
58207-19-5
(7S)-7-Chloro-7-deoxylincomycin hydrochloride
L-threo-alpha-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-((((2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl)carbonyl)amino)-1-thio-, monohydrochloride
L-threo-alpha-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(((1-methyl-4-propyl-2-pyrrolidinyl)carbonyl)amino)-1-thio-, (2S-trans)-, monohydrochloride
ZydaClin
Sobelin
(2S,4R)-N-((1S,2S)-2-CHLORO-1-((2R,3R,4S,5R,6R)-3,4,5-TRIHYDROXY-6-(METHYLTHIO)TETRAHYDRO-2H-PYRAN-2-YL)PROPYL)-1-METHYL-4-PROPYLPYRROLIDINE-2-CARBOXAMIDE HYDROCHLORIDE
Antirobe vet.
Clindamycin HCl (Dalacin)
Clindamycin 1000 microg/mL in Acetonitrile
D02132
CAS-21462-39-5