Sodium (3R,5R)-7-[(1S,2S,6R,8S,8aR)-2,6-dimethyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydro-1-naphthalenyl]-3,5-dihydroxyheptanoate（CAS号：75225-50-2）

洛伐他汀钠

基本信息

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CAS号

75225-50-2

分子式

C24H37NaO6

分子量

444.5 g/mol

化学分类

基础化工原料有机化学品羧酸类

基础化工原料有机化学品酯类

基础化工原料有机化学品醚类

精细化工产品表面活性剂阴离子表面活性剂

聚合物和塑料热塑性塑料聚烯烃

基本物理性质

熔点

154-160 ºC

SMILES

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CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC(CC(CC(=O)[O-])O)O)C.[Na+]

InChI

InChI=1S/C24H38O6.Na/c1-5-15(3)24(29)30-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-18(25)12-19(26)13-22(27)28;/h6-7,10,14-16,18-21,23,25-26H,5,8-9,11-13H2,1-4H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,18+,19+,20-,21-,23-;/m0./s1

InChIKey

LXZBFUBRYYVRQJ-AXHZAXLDSA-M

LogP

2.38090

复杂度

661

安全信息

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稳定性

Hygroscopic

同义词与引用数据

英文

Lovastatin sodium salt
6-a-Methylcompactin sodium
Lovastatinhydroxyacid(sodium)
Lovastatin Imp. B (EP); (3R,5R)-7-[(1S,2S,6R,8S,8aR)-2,6-Dimethyl-8-[[(2S)-2-methylbutanoyl]oxy]-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic Acid Sodium Salt; Lovastatin Imp. B (EP) as Sodium Salt; Lovastatin Hydroxy Acid Sodium Salt; Lovastatin Impurity B as Sodium Salt
L-154819
F82344
75225-50-2
1-NAPHTHALENEHEPTANOIC ACID, 1,2,6,7,8,8A-HEXAHYDRO-.BETA.,.DELTA.-DIHYDROXY-2,6-DIMETHYL-8-((2S)-2-METHYL-1-OXOBUTOXY)-, MONOSODIUM SALT, (.BETA.R,.DELTA.R,1S,2S,6R,8S,8AR)-
Lovastatin Sodium
Sodium mevinolinate
MB-530B
CHEMBL175236
HY-123672
Lovastatin EP Impurity B
(3R,5R)-7-[(1S,2S,6R,8S,8aR)-2,6-Dimethyl-8-[[(2S)-2-methylbutanoyl]oxy]-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic Acid Sodium Salt (Lovastatin Hydroxy Acid Sodium Salt)
sodium;(3R,5R)-7-[(1S,2S,6R,8S,8aR)-2,6-dimethyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
CS-0084179
Lovastatin hydroxy acid (sodium)
Sodium (3R,5R)-7-[(1S,2S,6R,8S,8aR)-2,6-dimethyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-beta,delta-dihydroxy-2,6-dimethyl-8-(2-methyl-1-oxobutoxy)-, sodium salt (1:1), (betaR,deltaR,1S,2S,6R,8S,8aR)-
1ST10320
MSD-803, sodium salt
UNII-LK08RY63S3
Mevinolin sodium
Lovastatin Hydroxy Acid, Sodium Salt
Lovastatin Na
Lovastatin hydroxy acid sodium salt
1-NAPHTHALENEHEPTANOIC ACID, 1,2,6,7,8,8A-HEXAHYDRO-.BETA.,.DELTA.-DIHYDROXY-2,6-DIMETHYL-8-(2-METHYL-1-OXOBUTOXY)-, SODIUM SALT (1:1), (.BETA.R,.DELTA.R,1S,2S,6R,8S,8AR)-
1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-beta,delta-dihydroxy-2,6-dimethyl-8-((2S)-2-methyl-1-oxobutoxy)-, monosodium salt, (betaR,deltaR,1S,2S,6R,8S,8aR)-
Mevinolinic acid (sodium)
LK08RY63S3

中文

洛伐他汀钠
1,2,6,7,8,8a-六氢-2,6-二甲基-8-(2-甲基丁酰氧基)-1-萘-3',5'-二羟基庚酸钠盐
4-(2,4-二甲基-苯基)-4-氧代丁酸
洛伐他汀羟基酸的钠盐标准品
洛伐他汀杂质B 标准品
洛伐他汀羟基酸钠盐
洛伐他汀羟酸钠盐
洛伐他汀杂质B

MDL号

MFCD00870475

常见问题

什么是洛伐他汀钠(CAS号：75225-50-2)？

洛伐他汀钠是一种化学合成的药物，其化学名为Sodium (3R,5R)-7-[(1S,2S,6R,8S,8aR)-2,6-二甲基-8-{[(2S)-2-甲基丁酰基]氧基}-1,2,6,7,8,8a-六氢-1-萘基]-3,5-二羟基庚酸酯，是一种用于降低血液中胆固醇水平的药物，属于HMG-CoA还原酶抑制剂。