Chirality

The main aim of the journal is to publish original contributions of scientific work on the role of chirality in chemistry and biochemistry in respect to biological, chemical, materials, pharmacological, spectroscopic and physical properties. Papers on the chemistry (physiochemical, preparative synthetic, and analytical), physics, pharmacology, clinical pharmacology, toxicology, and other biological aspects of chiral molecules will be published. Among the topics to be covered are: Asymmetric synthesis, including development and characterization of chiral catalysts and mechanistic aspects Isolation and structural elucidation of natural products Chiroptical spectroscopies (ECD, VCD, OR, ROA, CPL, …) covering experimental, instrumental, theoretical and computational aspects Homochirality and Spontaneous symmetry breaking in Nature Theoretical aspects of chirality phenomenon and optical activity Preparative and analytic separation of chiral molecules, including enantioselective chromatography and related techniques, liquid-liquid extractions, stereoisomer crystallizations Chiral Supramolecular chemistry and chirality on nanoscale Pharmacokinetics of chiral drugs (absorption, distribution, protein binding, biotransformation, etc.) Pharmacodynamics of chiral drugs (drug-receptor interactions, pharmacological and toxicological activity) Clinical pharmacology of chiral drugs (therapeutic index and response, bioavailability, adverse drug reactions, drug-drug interactions) Regulatory and legal aspects in the development, testing, and marketing of chiral compounds Stereochemistry of pesticides and other xenobiotics In addition to original research papers, the journal publishes brief reviews, short communications, tutorials, conference reports, and book reviews.