Facile copper-mediated activation of the N–H bond and the oxidative cleavage of the C2–C3 bond in 1H-2-phenyl-3-hydroxy-4-oxoquinoline
文献信息
Miklós Czaun, László Párkányi
The reaction of 1H-2-phenyl-3-hydroxy-4-oxoquinoline (PhquinH2; 1) with metallic copper leads to CuII(PhquinH)2 while in the presence of PPh3 to CuI2CuII(Phquin)2(PPh3)4. In the presence of tmeda and O2 ring cleavage occurs to give CuII(tmeda)(PhquinH)(N-baa). Both reactions represent a mild N–H activation and an oxidative C–C bond scission.
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Chemical Communications

ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry














