An electrochemiluminescent biosensor for uric acid based on the electrochemiluminescence of bis-[3,4,6-trichloro-2-(pentyloxycarbonyl)-phenyl] oxalate on an ITO electrode modified by an electropolymerized nickel phthalocyanine film

文献信息

发布日期 2008-03-20

DOI 10.1039/B716281B

影响因子 4.616

作者

Zhenyu Lin, Zhihuang Chen, Yan Liu, Jian Wang, Guonan Chen

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摘要

Nickel(II) tetrasulfophthalo-cyanine (NiTSPc) could be electrodeposited onto an indium tin oxide (ITO) electrode to form an electropolymerization film of NiTSPc. The electrochemiluminescent (ECL) behavior of bis-[3,4,6-trichloro-2-(pentyloxy-carbonyl)-phenyl] oxalate (BTPPO) on this modified electrode was investigated in detail. The emission of ECL of BTPPO can be greatly enhanced by hydrogen peroxide at this modified electrode. Thus, a new ECL biosensor for uric acid was developed based on the enzymatic reaction of uric acid in the presence of uricase to produce H2O2. The developed sensor has been used to detect uric acid in real serum samples, and the results compared well with those obtained by the routine method.

期刊推荐

Journal of Asian Natural Products Research

NDT & E International

Atomization and Sprays

Herald of the Russian Academy of Sciences

Medicinal Chemistry Research

Acta Metallurgica Sinica-English Letters

Journal of the Indian Institute of Science

Polycyclic Aromatic Compounds

Bioorganic & Medicinal Chemistry Letters

Critical Reviews in Solid State and Materials Sciences

来源期刊

Analyst

CiteScore: 7.8

自引率: 5.6%

年发文量: 653

Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.

An electrochemiluminescent biosensor for uric acid based on the electrochemiluminescence of bis-[3,4,6-trichloro-2-(pentyloxycarbonyl)-phenyl] oxalate on an ITO electrode modified by an electropolymerized nickel phthalocyanine film

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