Rational design of cationic cyclooligosaccharides as efficient gene delivery systems

文献信息

发布日期 2008-02-25
DOI 10.1039/B718672J
影响因子 6.222
作者

Alejandro Díaz-Moscoso, Patricia Balbuena, Marta Gómez-García, Carmen Ortiz Mellet, Juan M. Benito, Loïc Le Gourriérec, Christophe Di Giorgio, Pierre Vierling, Antonino Mazzaglia, Norberto Micali, Jacques Defaye, José M. García Fernández


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摘要

Self-assembled cyclodextrin (CD)–DNA nanoparticles (CDplexes) exhibiting transfection efficiencies significantly higher than PEI-based polyplexes have been prepared from homogeneous seven-fold symmetric polyaminothiourea amphiphiles constructed on a β-cyclodextrin scaffold.

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来源期刊

Chemical Communications

Chemical Communications
CiteScore: 8.6
自引率: 4.7%
年发文量: 2458

ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry

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