Fused tetracycles with a benzene or cyclohexadiene core: [2 + 2 + 2] cycloadditions on macrocyclic systems
文献信息
Sandra Brun, Lídia Garcia, Iván González, Anna Torrent, Anna Dachs, Anna Pla-Quintana, Teodor Parella, Anna Roglans
A series of fused tetracycles with a benzene or cyclohexadiene core (2a–h) is satisfactorily prepared by intramolecular [2 + 2 + 2] cycloadditions of triynic and enediynic macrocycles (1a–h) under RhCl(PPh3)3 catalysis; the enantioselective cycloaddition of macrocycles1b and 1e gives chiral tetracycles with moderate enantiomeric excess.
相关文献
Development and validation of a LC-MS/MS method for the simultaneous determination of cycloicaritin and its carbamate prodrug in rat plasma: application to pharmacokinetic study
Weiping Wang, Fengxiao Li, Jiaqi Fan, Shuo Gan, Jiaming Zhang, Tianhong Zhang
DOI: 10.1039/D3NJ04120D
Carboxymethylcellulose/layered double hydroxide dispersions for topical ocular delivery of non-steroidal anti-inflammatory drugs
Giuliana Mosconi, María Lina Formica, Santiago D. Palma, Ricardo Rojas
DOI: 10.1039/D3NJ04434C
Schiff base Mo(vi) complexes grafted on Merrifield resin as recyclable and efficient catalysts for the synthesis of pyrrole-2-ones
Qingmin Yan, Kanglong Wang, Wenhui Zhang, Mingwu Yu, Donglei Wei, Weili Wang, Gang Liu, Xiuwei Gao
DOI: 10.1039/D3NJ03510G
Enhanced room-temperature NO2 response of noble metal decorated α-Fe2O3/SnO2–rGO hybrids
Yaqing Zhang, Liang Zhao, Zhimin Yang, Yunpeng Xing, Congcong Xin, Zefeng Wei, Teng Fei, Sen Liu, Tong Zhang
DOI: 10.1039/D3NJ04531E
Conductive single-walled carbon nanotubes synthesized using a Fe–Mo/MgO catalyst for LiNi0.5Co0.2Mn0.3O2 lithium-ion batteries
Ziting Guo, Qingmei Xiao, Jinchao Huang, Shengwen Zhong
DOI: 10.1039/D3NJ04345B
Sorghum-derived porous carbon for outstanding green supercapacitors
Fuming Zhang, Hongchao Lang, Jinggao Wu, Jing Huang
DOI: 10.1039/D3NJ04881K
A novel approach towards synthesis of benzothiazoles and benzimidazoles: Eosin Y-catalyzed photo-triggered C–S and C–N bond formation
Khushbu Rajput, Vishal Singh, Arsala Kamal, Himanshu Kumar Singh, Sundaram Singh, Vandana Srivastava
DOI: 10.1039/D3NJ04374F
ZIF-8-based core/shell nanocarriers for relieving multidrug resistance in cancer therapy
Jinsong Gong, Xiaobin Li, Shaoping Li, Man Xu
DOI: 10.1039/D3NJ03775D
Screening and investigation of a short antimicrobial peptide: AVGAV
Yang Cao, Linlin Kang, Yumei Wang, Zekai Ren, Han Wu, Xin Liu
DOI: 10.1039/D3TB01672B
您可能还喜欢
6-氯-2H-1,4-苯并噁嗪-3(4H)-酮(CAS号:7652-29-1)应用于哪些行业?
6-氯-2H-1,4-苯并噁嗪-3(4H)-酮主要应用于医药、农药和聚合物等领域。在医药领域,该化合物可用于合成抗菌药物;在农药领域,可用作杀虫剂的中间体;在聚...
活性氧化铝(CAS号:1302-74-5)应用于哪些行业?
活性氧化铝广泛应用于医药、聚合物、传感器、半导体和催化等领域。在医药行业,活性氧化铝用作吸附剂和干燥剂,有助于去除杂质和水分。在聚合物行业,它用作增白剂和抗结块...
什么是硅胶(CAS号:112926-00-8)?
硅胶(Silica gel, pptd.,cryst.-free)是一种无定形、多孔的硅酸盐材料,主要成分为二氧化硅(SiO₂)。其结构由硅氧四面体构成,通过酸...
二乙基甲基一氢硅烷(CAS号:760-32-7)的主要用途是什么?
二乙基甲基一氢硅烷主要用于有机合成、表面处理以及作为溶剂。它还被用作合成其他硅烷化合物的原料,以及在涂料、粘合剂和密封剂中的应用。
在合成中是否有N-花生四烯酰基甘氨酸(CAS号:179113-91-8)的替代品?
在合成过程中,可以考虑使用类似结构的化合物作为替代品,例如N-亚油酰基甘氨酸或N-花生二烯酰基甘氨酸。这些替代品在结构上有类似的双键位置,但可能具有不同的物理化...
在合成中是否有1-(4-甲氧基苯基)丙烷-1,2-二酮(CAS号:10557-27-4)的替代品?
在合成过程中,可以考虑使用类似结构的化合物作为替代品,例如1-(3-甲氧基苯基)丙烷-1,2-二酮或1-(4-羟基苯基)丙烷-1,2-二酮。这些替代品具有相似的...
N-(4-氨基-1-苄基-3-羟基-5-苯基戊基)-3-甲基-2-(2-氧代四氢嘧啶-1-基)-丁酰胺 5-氧代吡咯烷-2-甲酸(CAS号:192726-06-0)通常如何合成?
该化合物通常通过一系列复杂的有机合成步骤获得。首先,通过芳香族化合物的羟基化反应获得羟基化产物,然后通过酰化反应形成酰胺中间体,最后通过环化反应得到目标产物。常...
(S)-2-氨基-3-喹啉-2-丙酸(CAS号:161513-46-8)的市场或研究趋势如何?
该化合物作为生物活性化合物,尤其是在药物化学领域表现出色。近年来,随着对新型抗炎、抗病毒和抗癌药物的研究增加,其市场和研究趋势持续增长。此外,其在神经科学领域的...
核黄素磷酸钠(CAS号:130-40-5)安全吗?
核黄素磷酸钠在常规使用条件下安全,但高剂量可能引起刺激性反应。操作时需佩戴防护手套和护目镜,避免吸入粉尘。若接触皮肤或眼睛,应立即用大量清水冲洗。急救时需根据接...
盐酸丙胺卡因杂质A(EP) 标准品(CAS号:19281-31-3)通常如何合成?
盐酸丙胺卡因杂质A(EP) 标准品可通过重氮化反应和随后的酰胺化反应合成。首先,利用氯化反应将苯环上的氢原子转化为氯原子,然后通过芳香族重氮化反应引入氨基,最后...
来源期刊
Chemical Communications

ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry











![Methyl 4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)bicyclo[2.2.2]octane-1-carboxylate structure Methyl 4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)bicyclo[2.2.2]octane-1-carboxylate structure](https://cnstatic.chemtradehub.com/structs/943/943845-74-7-b7e5.webp)


