Study of the Beckmann rearrangement of acetophenone oxime over porous solids by means of solid state NMR spectroscopy
文献信息
Ana Belen Fernandez, Ines Lezcano-Gonzalez, Mercedes Boronat, Teresa Blasco, Avelino Corma
The Beckmann rearrangement of acetophenone oxime using zeolite H-beta and silicalite-N as catalysts has been investigated by means of 15N and 13C solid state NMR spectroscopy in combination with theoretical calculations. The results obtained show that the oxime is N-protonated at room temperature on the acid sites of zeolite H-beta. At reaction temperatures of 423 K or above, the two isomeric amides, acetanilide and N-methyl benzamide (NMB) are formed, and interact with the Brønsted acid sites of zeolite H-beta through hydrogen bonds. The presence of residual water hydrolyzes the two amides, while larger amounts inhibit the formation of NMB and cause the total hydrolysis of the acetanilide. Over siliceous zeolite silicalite-N, containing silanol nests as active sites, the oxime is adsorbed through hydrogen bonds and only acetanilide is formed at reaction temperatures of 423 K or above. In the presence of water, the reaction starts at 473 K, still being very selective up to 573 K, and the amide is partially hydrolyzed only above this temperature .
期刊推荐

Russian Journal of Coordination Chemistry

Organic Process Research & Development

Journal of Natural Medicines

Russian Journal of Organic Chemistry

Russian Journal of Bioorganic Chemistry

Russian Journal of General Chemistry

New Journal of Chemistry

Current Opinion in Colloid & Interface Science

Chemistry Education Research and Practice

Nature Medicine
相关文献
Low quantum efficiency of μ-oxo iron bisporphyrin photocatalysts explained with femtosecond M-edge XANES
Kori M. Sye, Clare A. Leahy, Josh Vura-Weis
DOI: 10.1039/D2CY01081J
In situ modification of metal electrode by integrated microbial corrosion and microbial mineralization using Shewanella oneidensis for efficient oxygen evolution
Yang-Chun Yong, Jian-Li Mi
DOI: 10.1039/D2CY01981G
Highly efficient and durable solar thermal energy harvesting via scalable hierarchical coatings inspired by stony corals
Juan F. Torres, Kaoru Tsuda, Yasushi Murakami, Yifan Guo, Sahar Hosseini, Charles-Alexis Asselineau, Mahdiar Taheri, Kurt Drewes, Wojciech Lipiński, Joe Coventry
DOI: 10.1039/D1EE03028K
Amphiphilic stilbene derivatives attenuate the neurotoxicity of soluble Aβ42 oligomers by controlling their interactions with cell membranes
Zhengxin Yu, Weijie Guo, Shrey Patel, Hong-Jun Cho, Liang Sun
DOI: 10.1039/D2SC02654F
Nitrile hydrogenation to secondary amines under ambient conditions over palladium–platinum random alloy nanoparticles
Yoshihide Nishida, Chandan Chaudhari, Hiroshi Yamada, Takaaki Toriyama, Tomokazu Yamamoto, Susan Meñez Aspera, Hiroshi Nakanishi, Katsutoshi Nagaoka
DOI: 10.1039/D1CY02302K
Highly-oxidised, sulfur-rich, mixed-valence vanadium(iv/v) complexes
Michelle K. Taylor, David J. Evans, Charles G. Young
DOI: 10.1039/B610036H
Metal directed assembly of ditopic containers and their complexes with alkylammonium salts
Edoardo Menozzi, Julius Rebek Jr.
DOI: 10.1039/B509189F
Polypropylene fiber supported ionic liquids for the conversion of fructose to 5-hydroxymethylfurfural under mild conditions
Xian-Lei Shi, Min Zhang, Yongdan Li, Wenqin Zhang
DOI: 10.1039/C3GC41565A
Easy conjugations between molecules via copper-catalyzed reactions of ortho-aromatic diamines with ketones
Haijun Yang, Yunhe Jin, Yuyang Jiang
DOI: 10.1039/C3GC41585F
您可能还喜欢
4-((4-甲基哌嗪-1-基)甲基)苯硼酸(CAS号:763120-62-3)的市场或研究趋势如何?
随着有机硼化学的发展,该化合物在催化、药物合成、材料科学等领域展现出潜在的应用价值。近年来,其在药物前体合成中的应用越来越受到关注。市场趋势显示,随着科研投入的...
如何储存2,4,5-三甲基-1-硝基苯(CAS号:610-91-3)?
2,4,5-三甲基-1-硝基苯应储存在阴凉、干燥且通风良好的地方,避免阳光直射。储存在密封的金属容器中,远离火源和热源。储存温度应控制在25°C以下,湿度不宜过...
处理2,5-二碘噻吩(CAS号:625-88-7)时应注意哪些实验室安全事项?
在处理2,5-二碘噻吩时,应穿戴适当的个人防护装备(PPE),包括实验室外套、手套和防护眼镜。在通风橱中进行操作以避免吸入蒸气。如果发生泄漏,应立即疏散人员并使...
在合成中是否有6-bromo-3-chloro-1H-indole(CAS号:57916-08-2)的替代品?
在合成6-溴-3-氯-1H-吲哚(CAS号:57916-08-2)时,可以考虑使用一些类似的化合物作为替代品,如6-氯-3-氯-1H-吲哚或3-氯-1H-吲哚,...
在合成中是否有(R)-(-)-1-(1-萘基)乙基异氰酸酯(CAS号:42340-98-7)的替代品?
可以考虑使用类似结构的化合物,如1-[(1R)-1-(2-氨基乙基)萘-1-基]乙基异氰酸酯作为替代品。此外,还可以寻找其他类型的异氰酸酯衍生物,如苯基异氰酸酯...
3-氨基苯甲酰苯胺(CAS号:14315-16-3)适用哪些法规指南?
3-氨基苯甲酰苯胺适用于多项法规指南,包括但不限于GHS(全球化学品统一分类和标签制度)分类为皮肤腐蚀/刺激类别2,以及潜在的皮肤过敏性类别1。在欧盟地区,它受...
β-环柠檬醛-D5(CAS号:26309-95-5)通常如何合成?
β-环柠檬醛-D5可通过不对称合成方法获得。常见的合成路线包括以环己酮为原料,经过选择性氧化、还原、保护基引入等步骤,最终得到目标化合物。该合成过程中通常使用多...
如何处理含有BIO-1211(CAS号:187735-94-0)的废料?
对于含有BIO-1211(CAS号:187735-94-0)的废料,首先应进行分类收集,确保符合环保要求。然后,可以考虑通过焚烧或其他专业处理方法进行处置。在处...
如何处理含有4-氯-2-氟-3-甲基苯酚(CAS号:1351668-24-0)的废料?
含有该化合物的废液应收集至专用容器中,避免与其他化学品混合。可采用焚烧或送交专业废弃物处理公司处理。处理过程中需遵守当地环保法规,确保不产生二次污染。处理前应进...
来源期刊
Physical Chemistry Chemical Physics

Physical Chemistry Chemical Physics (PCCP) is an international journal co-owned by 19 physical chemistry and physics societies from around the world. This journal publishes original, cutting-edge research in physical chemistry, chemical physics and biophysical chemistry. To be suitable for publication in PCCP, articles must include significant innovation and/or insight into physical chemistry; this is the most important criterion that reviewers and Editors will judge against when evaluating submissions. The journal has a broad scope and welcomes contributions spanning experiment, theory, computation and data science. Topical coverage includes spectroscopy, dynamics, kinetics, statistical mechanics, thermodynamics, electrochemistry, catalysis, surface science, quantum mechanics, quantum computing and machine learning. Interdisciplinary research areas such as polymers and soft matter, materials, nanoscience, energy, surfaces/interfaces, and biophysical chemistry are welcomed if they demonstrate significant innovation and/or insight into physical chemistry. Joined experimental/theoretical studies are particularly appreciated when complementary and based on up-to-date approaches.




