Microenvironment-switchable singlet oxygen generation by axially-coordinated hydrophilic ruthenium phthalocyanine dendrimers
文献信息
Uwe Hahn, Francesca Setaro, Xavier Ragàs, Angus Gray-Weale, Santi Nonell, Tomas Torres
A series of new metallodendrimers built around a ruthenium phthalocyanine core has been prepared. Employing a convergent synthetic strategy, pyridine-containing ligands were prepared and then assembled onto the ruthenium phthalocyanine through axial ligand coordination. The growing shell of oligoethylene glycol chains surrounding the lipophilic core allows solubilisation in water. Photophysical studies show that all the metallodendrimers are strongly phosphorescent and the deactivation pathway of their triplet state depends on the medium in which the compounds are dissolved. On one hand, quenching of the triplet state by the dendritic shell is observed and found to be substantially enhanced in aqueous media. On the other, the dendrimer shields the phthalocyanine from oxygen. This notwithstanding, the phthalocyanines are able to generate singlet oxygen in less polar environments such as in CHCl3 or THF solution, while in water the generation of singlet oxygen is almost completely switched off.
期刊推荐

Organic Process Research & Development

Russian Journal of Bioorganic Chemistry

Journal of Natural Medicines

Chemical Communications

Russian Chemical Bulletin

Russian Journal of Applied Chemistry

Saudi Pharmaceutical Journal

Nature Medicine

Journal of Saudi Chemical Society

Current Opinion in Colloid & Interface Science
相关文献
Acidity constant and DFT-based modelling of pH-responsive alendronate loading and releasing on propylamine-modified silica surface
Khalid Ahmed, Shaukatali Najikhan Inamdar, Nashiour Rohman, Adam A. Skelton
DOI: 10.1039/D0CP04498A
Magnetic anisotropy in YbIII complex candidates for molecular qubits: a theoretical analysis
Martín Amoza, Silvia Gómez-Coca, Eliseo Ruiz
DOI: 10.1039/D0CP05422D
TD-DFT simulations of K-edge resonant inelastic X-ray scattering within the restricted subspace approximation
Vinícius Vaz da Cruz, Sebastian Eckert
DOI: 10.1039/D0CP04726K
Molecular perspective on charge-tunable adsorption of volatile organic compounds on carbon nanotubes
Bin Li, Changwen Mi
DOI: 10.1039/D0CP05729K
Free ions in kerosene-based ferrofluid detected by impedance spectroscopy
F. Batalioto, A. F. C. Campos, A. M. Figueiredo Neto
DOI: 10.1039/D0CP05865C
Comparative study of the elastic properties of adamantane and 1-chloroadamantane at high pressure and different temperatures and at order–disorder transitions
Elena L. Gromnitskaya, Igor V. Danilov, Vadim V. Brazhkin
DOI: 10.1039/D0CP04550K
The quantitative impact of fluid vs. solid interfaces on the catalytic performance of pickering emulsions
Sebastian Stock, Annika Schlander, Maresa Kempin, Ramsia Geisler, Dmitrij Stehl, Kai Spanheimer, Nicole Hondow, Stuart Micklethwaite, Ariane Weber, Reinhard Schomäcker, Anja Drews, Markus Gallei, Regine von Klitzing
DOI: 10.1039/D0CP06030E
Inverse halogen dependence in anion 13C NMR
Renan V. Viesser, Cláudio F. Tormena
DOI: 10.1039/D0CP05891B
A general approach to study molecular fragmentation and energy redistribution after an ionizing event
Suvasthika Indrajith, Alicja Domaracka, Patrick Rousseau, Bernd A. Huber, Paola Bolognesi, Robert Richter, Lorenzo Avaldi, Marta Łabuda
DOI: 10.1039/D0CP04890A
Collaboration between a Pt-dimer and neighboring Co–Pd atoms triggers efficient pathways for oxygen reduction reaction
Sheng Dai, Dinesh Bhalothia, Jyh-Pin Chou
DOI: 10.1039/D0CP05205A
您可能还喜欢
什么是2-Bromo-1-(pyrimidin-2-yl)ethanone hydrobromide(CAS号:1588441-02-4)?
2-Bromo-1-(pyrimidin-2-yl)ethanone hydrobromide是一种有机化合物,分子式为C6H5Br2N2O2。它是一种溴代化合...
在合成中是否有1-正-丁基-3-甲基咪唑鎓三氟甲烷磺酸盐(CAS号:174899-66-2)的替代品?
在合成中,可以考虑使用1-正-丁基-3-甲基咪唑鎓溴酸盐或1-正-丁基-3-甲基咪唑鎓氯酸盐作为替代品。这些化合物在性能上与1-正-丁基-3-甲基咪唑鎓三氟甲烷...
2-methyl-5-thiophen-2-ylfuran-3-carboxylic acid(CAS号:651005-90-2)的市场或研究趋势如何?
目前,2-methyl-5-thiophen-2-ylfuran-3-carboxylic acid的研究主要集中在药物化学和新型材料领域。随着生物医药和有机合...
格列吡嗪杂质H(CAS号:13554-93-3)的主要用途是什么?
格列吡嗪杂质H主要作为药物中间体或副产物存在,并无特定的工业应用。在药物生产中,它可能需要被处理掉以保证最终药物的质量。
如何储存(9ci)-4-甲氧基-1H-苯并咪唑-2-乙腈(CAS号:317817-41-7)?
(9ci)-4-甲氧基-1H-苯并咪唑-2-乙腈应储存在阴凉、干燥、通风良好的地方,避免阳光直射。使用密封的玻璃或塑料容器储存,并确保容器的密封性良好,以防止挥...
4,5,9,10-四氢苯芘(CAS号:781-17-9)应用于哪些行业?
4,5,9,10-四氢苯芘在医药行业用于作为某些药物的中间体,在聚合物行业用作添加剂提升材料的热稳定性,在传感器领域作为传感器的敏感材料,在半导体行业中用作掺杂...
处理叶酸-D4(CAS号:171777-72-3)时应注意哪些实验室安全事项?
处理叶酸-D4时应佩戴个人防护装备(PPE),如手套和实验服。操作应在通风橱内进行,以避免吸入蒸汽或粉尘。如果不慎泄露,应立即用大量清水冲洗,并通知安全人员。参...
如何处理含有6-溴-2-(三氟乙酰基)-1,2,3,4-四氢异喹啉(CAS号:252331-63-8)的废料?
含有该化合物的废料应收集到专用的容器中,并进行密封以防止挥发和泄漏。在处理前,需进行危险性评估,以确定是否需要进行化学处理。最终处置需遵循当地的危险废物管理规定...
4,5-二氟-2-甲氧基苯甲醛(CAS号:145742-34-3)的主要用途是什么?
4,5-二氟-2-甲氧基苯甲醛主要用作有机合成中的中间体,特别是在制药和农药领域。它可以作为合成其他有机化合物的原料。
5-溴-6-三氟甲基吲哚(CAS号:1198475-24-9)安全吗?
5-溴-6-三氟甲基吲哚作为一种化学试剂,具有一定的毒性,需要在通风橱中操作,并采取适当的安全措施以避免吸入、皮肤接触和眼睛刺激。应避免与皮肤和眼睛直接接触,并...
来源期刊
Physical Chemistry Chemical Physics

Physical Chemistry Chemical Physics (PCCP) is an international journal co-owned by 19 physical chemistry and physics societies from around the world. This journal publishes original, cutting-edge research in physical chemistry, chemical physics and biophysical chemistry. To be suitable for publication in PCCP, articles must include significant innovation and/or insight into physical chemistry; this is the most important criterion that reviewers and Editors will judge against when evaluating submissions. The journal has a broad scope and welcomes contributions spanning experiment, theory, computation and data science. Topical coverage includes spectroscopy, dynamics, kinetics, statistical mechanics, thermodynamics, electrochemistry, catalysis, surface science, quantum mechanics, quantum computing and machine learning. Interdisciplinary research areas such as polymers and soft matter, materials, nanoscience, energy, surfaces/interfaces, and biophysical chemistry are welcomed if they demonstrate significant innovation and/or insight into physical chemistry. Joined experimental/theoretical studies are particularly appreciated when complementary and based on up-to-date approaches.



![[2-(Benzyloxy)-3-bromo-5-methylphenyl]boronic acid structure [2-(Benzyloxy)-3-bromo-5-methylphenyl]boronic acid structure](https://cnstatic.chemtradehub.com/structs/870/870777-20-1-24ac.webp)
![2-(Methylsulfonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole structure 2-(Methylsulfonyl)-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole structure](https://cnstatic.chemtradehub.com/structs/122/1226781-80-1-09d5.webp)