Synthesis and antibacterial characterization of gemini surfactant monomers and copolymers

文献信息

发布日期 2012-01-30

DOI 10.1039/C2PY00558A

影响因子 5.582

作者

Yi Zhang, Mingming Ding, Lijuan Zhou, Hong Tan, Jiehua Li, Huining Xiao, Jianshu Li, James Snow

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摘要

A series of novel quaternary ammonium gemini monomers with broad-spectrum antibacterial activities were synthesized with a facile method. The surface tensions at various concentrations of gemini monomers were measured. The antibacterial and antifungal activities of these gemini monomers were evaluated by quantifying the minimal inhibitory concentration (MIC). The results indicated that the quaternary ammonium gemini monomers showed lower surface tensions and good activity against a broad spectrum of Gram-positive and Gram-negative bacteria as well as fungi, compared with a commercially available n-dodecyl-trimethylammonium bromide (DTAB). These monomers could be easily copolymerized with N-(3-aminopropyl) methacrylamide hydrochloride (APMA) using free radical polymerization to develop novel antibacterial polymers.

期刊推荐

Catalysis Communications

Current Organic Synthesis

Molecular Cancer Therapeutics

Nature Materials

Organic Letters

Catalysis Surveys from Asia

Phytochemistry Reviews

Physics of Life Reviews

Nature Methods

Molecular Pharmaceutics

来源期刊

Polymer Chemistry

CiteScore: 8.6

自引率: 7.3%

年发文量: 457

Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.

Synthesis and antibacterial characterization of gemini surfactant monomers and copolymers

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